The epicardium, previously viewed as a passive outer layer around the heart, is now
recognized as an essential component in development, regeneration, and repair. In this …

Cardiovascular disease (CVD) has become a severe threat to human health, with morbidity
and mortality increasing yearly and gradually becoming younger. When the disease …

The epicardium, a mesothelial cell tissue that encompasses vertebrate hearts, supports
heart regeneration after injury through paracrine effects and as a source of multipotent …

Congenital heart defects occur in almost 80% of patients with CHARGE syndrome, a
sporadically occurring disease causing craniofacial and other abnormalities due to …

Abstract Tbx18, Wt1, and Tcf21 have been identified as epicardial markers during the early
embryonic stage. However, the gene markers of mature epicardial cells remain unclear …

Brain pericytes are one of the critical cell types that regulate endothelial barrier function and
activity, thus ensuring adequate blood flow to the brain. The genetic pathways guiding …

Ischaemic heart disease is a global healthcare challenge with high morbidity and mortality.
Early revascularisation in acute myocardial infarction has improved survival; however …

The epicardium, a mesothelial cell tissue that encompasses vertebrate hearts, supports
heart regeneration after injury through paracrine effects and as a source of multipotent …

Brain pericytes are critical for regulating endothelial barrier function and activity, thus
ensuring adequate blood flow to the brain. The genetic pathways guiding undifferentiated …

Ischemic heart disease caused by occlusion of coronary vessels leads to the death of
downstream tissues, resulting in a fibrotic scar that cannot be resolved. In contrast to the …