Biological markers for pulpal inflammation: a systematic review

DK Rechenberg, JC Galicia, OA Peters - PloS one, 2016 - journals.plos.org
Background and Objective Pulpitis is mainly caused by an opportunistic infection of the pulp
space with commensal oral microorganisms. Depending on the state of inflammation …

Inflammation and regeneration in the dentin-pulp complex: a double-edged sword

PR Cooper, MJ Holder, AJ Smith - Journal of endodontics, 2014 - Elsevier
Dental tissue infection and disease result in acute and chronic activation of the innate
immune response, which is mediated by molecular and cellular signaling. Different cell …

The application of tissue engineering to regeneration of pulp and dentin in endodontics

M Nakashima, A Akamine - Journal of endodontics, 2005 - Elsevier
Caries, pulpitis, and apical periodontitis increase health care costs and attendant loss of
economic productivity. They ultimately result in premature tooth loss and therefore …

Pulp inflammation diagnosis from clinical to inflammatory mediators: a systematic review

M Zanini, E Meyer, S Simon - Journal of endodontics, 2017 - Elsevier
Introduction Similar to other tissues, the dental pulp mounts an inflammatory reaction as a
way to eliminate pathogens and stimulate repair. Pulp inflammation is prerequisite for dentin …

Human dental pulp stem cells improve left ventricular function, induce angiogenesis, and reduce infarct size in rats with acute myocardial infarction

C Gandia, ANA Arminan, JM García-Verdugo… - Stem …, 2008 - academic.oup.com
Human dental pulp contains precursor cells termed dental pulp stem cells (DPSC) that show
self-renewal and multilineage differentiation and also secrete multiple proangiogenic and …

Current state and challenges of the global outcomes of dental caries research in the meta-omics era

DG Moussa, P Ahmad, TA Mansour… - Frontiers in Cellular and …, 2022 - frontiersin.org
Despite significant healthcare advances in the 21st century, the exact etiology of dental
caries remains unsolved. The past two decades have witnessed a tremendous growth in our …

A critical analysis of research methods and experimental models to study pulpitis

R Richert, M Ducret, B Alliot‐Licht… - International …, 2022 - Wiley Online Library
Pulpitis is the inflammatory response of the dental pulp to a tooth insult, whether it is
microbial, chemical, or physical in origin. It is traditionally referred to as reversible or …

Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules

JL Baker, JT Morton, M Dinis, R Alvarez… - Genome …, 2021 - genome.cshlp.org
Dental caries, the most common chronic infectious disease worldwide, has a complex
etiology involving the interplay of microbial and host factors that are not completely …

Effects of VEGF and FGF2 on the revascularization of severed human dental pulps

EM Mullane, Z Dong, CM Sedgley… - Journal of dental …, 2008 - journals.sagepub.com
The long-term outcome of replanted avulsed permanent teeth is frequently compromised by
lack of revascularization, resulting in pulp necrosis. The purpose of this study was to …

Caries induced cytokine network in the odontoblast layer of human teeth

OV Horst, JA Horst, R Samudrala, BA Dale - BMC immunology, 2011 - Springer
Background Immunologic responses of the tooth to caries begin with odontoblasts
recognizing carious bacteria. Inflammatory propagation eventually leads to tooth pulp …