Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Understanding immunity in humans to Group A Streptococcus (Strep A) is critical for the
development of successful vaccines to prevent the morbidity and mortality attributed to Strep …

The fine structures of Fc N-glycans can modulate the effector functions of IgG antibodies. It
has been demonstrated that lack of the core fucose on the Fc N-glycans leads to drastic …

Recent work from several laboratories has demonstrated that proteolytic mechanisms
significantly contribute to the molecular interplay between Streptococcus pyogenes, an …

The group A streptococcus (GAS)(Streptococcus pyogenes) is among the most common and
versatile of human pathogens. It is responsible for a wide spectrum of human diseases …

The endo-β-N-acetylglucosaminidases (ENGases) are an enzyme class (EC 3.2. 1.96)
produced by a range of organisms, ranging from bacteria, through fungi, to higher order …

The development of bacterial disease has been likened to a'molecular arms race', in which
the host tries to eliminate the bacteria, while the bacteria try to survive in the host. Although …

Aims This review is intended to update our previous discussion on the chemoenzymatic
synthesis of carbohydrates and glycoconjugates,(1) with new emphasis placed on …

Bacterial biofilms represent multicellular communities embedded in a matrix of extracellular
polymeric substances, conveying increased resistance against environmental stress factors …

Group A streptococcus (Streptococcus pyogenes) is an exclusively human pathogen that
causes a wide spectrum of diseases ranging from pharyngitis, to impetigo, to toxic shock, to …