Cryo-soft X-ray tomography is an imaging technique that addresses the need for mesoscale
imaging of cellular ultrastructure of relatively thick samples without the need for staining or …

Imaging techniques in structural cell biology are indispensable to understand cell
organization and machinery. In this frame, cryo soft X-ray tomography (cryo-SXT), a …

High-resolution and rapid imaging of host cell ultrastructure can generate insights toward
viral disease mechanism, for example for a severe acute respiratory syndrome coronavirus …

Cell proteostasis includes gene transcription, protein translation, folding of de novo proteins,
post‐translational modifications, secretion, degradation and recycling. By profiling the …

Epithelial intercellular adhesion molecule (ICAM)-1 is apically polarized, interacts with, and
guides leukocytes across epithelial barriers. Polarized hepatic epithelia organize their apical …

Morphometric measurements, such as quantifying cell shape, characterizing sub-cellular
organization, and probing cell–cell interactions, are fundamental in cell biology and clinical …

The diversity of living cells, in both size and internal complexity, calls for imaging methods
with adaptable spatial resolution. Soft x-ray tomography (SXT) is a three-dimensional …

T lymphocyte activation requires the formation of immune synapses (IS) with antigen-
presenting cells. The dynamics of membrane receptors, signaling scaffolds, microfilaments …

Viruses are obligate parasites that depend on a host cell for replication and survival.
Consequently, to fully understand the viral processes involved in infection and replication, it …

Multimodal imaging promises to revolutionize the understanding of biological processes
across scales in space and time by combining the strengths of multiple imaging techniques …