The role of neutrophil extracellular traps in cancer progression, metastasis and therapy

Y Chen, H Hu, S Tan, Q Dong, X Fan, Y Wang… - … Hematology & Oncology, 2022 - Springer
Neutrophil extracellular traps (NETs) released by activated neutrophils typically consist of
DNA-histone complexes and granule proteins. NETs were originally identified as a host …

CAFs orchestrates tumor immune microenvironment—A new target in cancer therapy?

C Zhang, Y Fei, H Wang, S Hu, C Liu, R Hu… - Frontiers in …, 2023 - frontiersin.org
Cancer immunotherapy has opened a new landscape in cancer treatment, however, the
poor specificity and resistance of most targeted therapeutics have limited their therapeutic …

Nanomedicine strategies for heating “cold” ovarian cancer (OC): next evolution in immunotherapy of OC

Y Yang, T Zhao, Q Chen, Y Li, Z Xiao… - Advanced …, 2022 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …

Cancer metastasis and treatment resistance: mechanistic insights and therapeutic targeting of cancer stem cells and the tumor microenvironment

EJ Kilmister, SP Koh, FR Weth, C Gray, ST Tan - Biomedicines, 2022 - mdpi.com
Cancer metastasis and treatment resistance are the main causes of treatment failure and
cancer-related deaths. Their underlying mechanisms remain to be fully elucidated and have …

Diarylheptanoids/sorafenib as a potential anticancer combination against hepatocellular carcinoma: the p53/MMP9 axis of action

A Elmetwalli, T Diab, AN Albalawi… - Naunyn-schmiedeberg's …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a serious and potentially fatal form of cancer associated
with liver damage. New anticancer drugs are increasingly needed due to the increasing …

[HTML][HTML] Immune cell membrane-based biomimetic nanomedicine for treating cancer metastasis

L Zhu, X Yu, T Cao, H Deng, X Tang, Q Lin… - … Pharmaceutica Sinica B, 2023 - Elsevier
Metastasis is the leading cause of cancer-related death. Despite extensive treatment, the
prognosis for patients with metastatic cancer remains poor. In addition to conventional …

Platelet-lymphocyte and neutrophil-lymphocyte ratios are prognostic markers for pheochromocytomas and paragangliomas

X Zhong, TW Su, Y Yang, L Ye, L Jiang… - The Journal of …, 2023 - academic.oup.com
Context Preoperative inflammatory markers, such as the neutrophil-lymphocyte ratio (NLR),
platelet-lymphocyte ratio (PLR), and lymphocyte-monocyte ratio (LMR), have recently been …

Therapeutic applications of nanoparticles targeting neutrophil and extracellular traps

N Rezaei, M Zadory, S Babity, S Marleau… - Journal of Controlled …, 2023 - Elsevier
Neutrophils, the most abundant leukocytes in human circulation, are key effectors and
regulators of both innate and adaptive immunity which migrate from the bloodstream to sites …

Di-(2-ethylhexyl) phthalate aggravates psoriasis-like skin lesions: In vitro and in vivo evaluation

Y Qian, L Zhu, J Chen, Y Zhou, Z Huang, L Liang… - Toxicology and Applied …, 2023 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP), which is a widely used phthalate (PAE), has
recently received public attention owing to it causing health problems. The aim of this study …

Tumor-infiltrating neutrophils and peripheral neutrophil-to-lymphocyte ratio conversely predicted the prognosis of patients with non-small cell lung cancer

R Yang, X Wang, C Ma, Z Zhang, N Liu, X Ma… - Cellular …, 2022 - Elsevier
Increasing evidence indicates that neutrophil-associated prognostic markers, such as, tumor-
associated neutrophils (TANs), neutrophil-to-T cell ratio (NTR) and neutrophil-to-lymphocyte …