Extracellular vesicles and their cells of origin: Open issues in autoimmune diseases

A Haghighitalab, M Dominici, MM Matin… - Frontiers in …, 2023 - frontiersin.org
The conventional therapeutic approaches to treat autoimmune diseases through
suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory …

Induced Pluripotent Stem Cell‐Derived Extracellular Vesicles Promote Wound Repair in a Diabetic Mouse Model via an Anti‐Inflammatory Immunomodulatory …

D Levy, SN Abadchi, N Shababi… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) derived from mesenchymal stem/stromal cells (MSCs) have
recently been explored in clinical trials for treatment of diseases with complex …

Effects of small extracellular vesicles derived from normoxia- and hypoxia-treated prostate cancer cells on the submandibular salivary gland epithelium in vitro

A Špilak, A Brachner, HP Friedl, A Klepe… - Tissue …, 2024 - Taylor & Francis
Small extracellular vesicles (sEVs) are an important part of intercellular communication.
They are phospholipid bilayer particles that carry active biomolecules such as proteins …

Harnessing Extracellular Vesicles for Stabilized and Functional IL-10 Delivery in Macrophage Immunomodulation

NA Saleh, MA Gagea, X Vitija, T Janovic, JC Schmidt… - bioRxiv, 2025 - biorxiv.org
Extracellular vesicles (EVs) are gaining recognition as promising therapeutic carriers for
immune modulation. We investigated the potential of EVs derived from HEK293FT cells to …

M2 macrophages secrete glutamate-containing extracellular vesicles to alleviate osteoporosis by reshaping osteoclast precursor fate

X Huang, Y Lan, J Shen, X Zhao, Y Zhou, W Wu… - Molecular Therapy, 2024 - cell.com
Osteoclast precursors (OCPs) are thought to commit to osteoclast differentiation, which is
accelerated by aging-related chronic inflammation, thereby leading to osteoporosis …