The neurobiology of irritable bowel syndrome

EA Mayer, HJ Ryu, RR Bhatt - Molecular psychiatry, 2023 - nature.com
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

The global prevalence of anxiety among medical students: a meta-analysis

T Tian-Ci Quek, W Wai-San Tam, B X. Tran… - International journal of …, 2019 - mdpi.com
Anxiety, although as common and arguably as debilitating as depression, has garnered less
attention, and is often undetected and undertreated in the general population. Similarly …

Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials

RT Liu, RFL Walsh, AE Sheehan - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
With growing interest in the gut microbiome, prebiotics and probiotics have received
considerable attention as potential treatments for depression and anxiety. We conducted a …

The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

[HTML][HTML] The central nervous system and the gut microbiome

G Sharon, TR Sampson, DH Geschwind… - Cell, 2016 - cell.com
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

Systematic review with meta‐analysis: the prevalence of anxiety and depression in patients with irritable bowel syndrome

M Zamani, S Alizadeh‐Tabari… - Alimentary pharmacology …, 2019 - Wiley Online Library
Background Irritable bowel syndrome (IBS) is a common and potential disabling functional
gastrointestinal disorder. Studies have revealed a possible association between IBS and …

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

Y Wu, GK Murray, EM Byrne, J Sidorenko… - Nature …, 2021 - nature.com
Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other
gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable …

Human intestinal barrier function in health and disease

J König, J Wells, PD Cani… - Clinical and …, 2016 - journals.lww.com
The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently
absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a …

[HTML][HTML] Atypical interoception as a common risk factor for psychopathology: A review

R Brewer, J Murphy, G Bird - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
The inadequacy of a categorial approach to mental health diagnosis is now well-recognised,
with many authors, diagnostic manuals and funding bodies advocating a dimensional, trans …

Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility

E Savarino, F Zingone, B Barberio… - United European …, 2022 - Wiley Online Library
Irritable bowel syndrome with diarrhoea (IBS‐D) and functional diarrhoea (FDr) are the two
major functional bowel disorders characterized by diarrhoea. In spite of their high …