Advances in Neuroimaging Biomarkers and Scoring

M Machie, LS de Vries, T Inder - Clinics in Perinatology, 2024 - perinatology.theclinics.com
Neuroimaging, particularly MRI, is widely used as the key modality in the diagnosis of
hypoxic-ischemic encephalopathy (HIE) in the setting of neonatal encephalopathy (NE) …

Hypothalamic volume is associated with age, sex and cognitive function across lifespan: a comparative analysis of two large population-based cohort studies

P Xu, S Estrada, R Etteldorf, D Liu, M Shahid… - …, 2025 - thelancet.com
Background Emerging findings indicate that the hypothalamus, the body's principal
homeostatic centre, plays a crucial role in modulating cognition, but comprehensive …

Individualized Neuroprognostication in Neonates With Hypoxic-Ischemic Encephalopathy Treated With Hypothermia

A Van Steenis, MN Cizmeci, F Groenendaal… - Neurology: Clinical …, 2025 - neurology.org
Background and Objectives To determine whether post-rewarming brain MRI enables
individualized domain-specific prediction of neurodevelopmental outcomes at 2 years of age …

Hypothalamic integrity is associated with age, sex and cognitive function across lifespan: A comparative analysis of two large population-based cohort studies

P Xu, S Estrada, R Etteldorf, D Liu, M Shahid, W Zeng… - medRxiv, 2024 - medrxiv.org
Background The hypothalamus is the body's principal homeostatic center. Emerging
findings from animal studies suggest that the hypothalamus could also play a crucial role in …

Resting-state functional connectivity in children cooled for neonatal encephalopathy

APC Spencer, M Goodfellow… - Brain …, 2024 - academic.oup.com
Therapeutic hypothermia improves outcomes following neonatal hypoxic-ischaemic
encephalopathy, reducing cases of death and severe disability such as cerebral palsy …

Hypoxic-Ischemic Encephalopathy (HIE) in Term and Near-Term Infants

K Mohammad, LS de Vries, G Meijler… - Neonatal Brain Injury: An …, 2025 - Springer
Hypoxic-ischemic encephalopathy (HIE) remains a major burden for infants, their families,
and society all over the world, while the incidence of HIE has fallen slightly in high-income …

[PDF][PDF] BRAIN COMMUNICATIONS

APC Spencer, M Goodfellow, E Chakkarapani… - 2024 - ore.exeter.ac.uk
Therapeutic hypothermia has considerably improved outcomes following neonatal hypoxic-
ischaemic encephalopathy (HIE) secondary to perinatal asphyxia. Cooled infants are at …

[PDF][PDF] Children cooled for neonatal encephalopathy without cerebral palsy retain healthy resting-state static and dynamic functional connectivity

APC Spencer, M Goodfellow, E Chakkarapani… - scholar.archive.org
Therapeutic hypothermia improves outcomes following neonatal hypoxic-ischaemic
encephalopathy (HIE), reducing cases of death and severe disability such as cerebral palsy …

Cerebellar growth, volume and diffusivity in children cooled for neonatal encephalopathy without cerebral palsy

CQ Wu, FM Cowan, S Jary, M Thoresen… - Scientific Reports, 2023 - nature.com
Children cooled for HIE and who did not develop cerebral palsy (CP) still underperform at
early school age in motor and cognitive domains and have altered supra-tentorial brain …