Bone marrow mesenchymal stem cells (BMSCs), which were first discovered in bone
marrow, are capable of differentiating into osteoblasts, chondrocytes, fat cells, and even …

Biomarkers are essential tools in clinical research and practice. Useful biomarkers must
combine good measurability, validated association with biological processes or outcomes …

Long non-coding RNAs (lncRNAs) have emerged as promising novel modulators during
osteogenesis in mesenchymal stem cells (MSCs). Enhanced SATB2 has been …

The alteration of age‐related molecules in the bone marrow microenvironment is one of the
driving forces in osteoporosis. These molecules inhibit bone formation and promote bone …

Human mesenchymal stem cell (hMSC)-derived exosomes have shown regenerative
effects, but their role in osteogenesis and the underlying mechanism are yet to be …

Damage to cells and tissues is one of the driving forces of aging and age‐related diseases.
Various repair systems are in place to counteract this functional decline. In particular, the …

Mesenchymal stem cells (mesenchymal stromal cells, MSC) are multipotent stem cells that
can differentiate into cells of at least three mesodermal lineages, namely adipocytes …

Mesenchymal stem cells (MSCs) and MSC‐derived small extracellular vesicles (sEVs) are
promising candidates for cell‐based and cell‐free regenerative medicine, respectively. By …

Osteoporosis, or bone loss, is a progressive, systemic skeletal disease that affects millions of
people worldwide. Osteoporosis is generally age related, and it is underdiagnosed because …

Bone formation and regeneration is a multistep complex process crucially determined by the
formation of blood vessels in the growth plate region. This is preceded by the expression of …