Melatonin is ubiquitous molecule with wide distribution in nature and is produced by many
living organisms. In human beings, pineal gland is the major site for melatonin production …

Obesity and its complications have become a prominent global public health problem that
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …

Alzheimer's disease (AD) is an age-related neurodegenerative disease with multiple
predisposing factors and complicated pathogenesis. Aβ peptide is one of the most important …

Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

Experimental studies have proven that melatonin has many beneficial pleiotropic actions.
The aim of this study was to assess melatonin efficacy in patients with metabolic syndrome …

Alzheimer's disease (AD) is a highly complex neurodegenerative disorder of the aged that
has multiple factors which contribute to its etiology in terms of initiation and progression. This …

Highlights•Pathways controlling melatonin secretion are complex.•There are various causes
of melatonin disturbance.•Evaluation of melatonin secretion clinically requires long time …

Melatonin, an endogenously synthesized indolamine, is a powerful antioxidant exerting
beneficial action in many pathological conditions. Melatonin protects from oxidative stress in …

The metabolic syndrome (MS) is a collection of risk factors for cardiovascular disease,
including obesity, hypertension, hyperinsulinemia, glucose intolerance and dyslipidemia …

Melatonin, a pleiotropic hormone, has many regulatory effects on the circadian and
seasonal rhythms, sleep and body immune system. It is used in the treatment of blind …