[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …
for clinical diagnostic applications and in basic research areas such as cognitive …
The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …
In vivo imaging of phosphocreatine with artificial neural networks
Phosphocreatine (PCr) plays a vital role in neuron and myocyte energy homeostasis.
Currently, there are no routine diagnostic tests to noninvasively map PCr distribution with …
Currently, there are no routine diagnostic tests to noninvasively map PCr distribution with …
Non-invasive mapping of brown adipose tissue activity with magnetic resonance imaging
Z Cai, Q Zhong, Y Feng, Q Wang, Z Zhang, C Wei… - Nature …, 2024 - nature.com
Thermogenic brown adipose tissue (BAT) has a positive impact on whole-body metabolism.
However, in vivo mapping of BAT activity typically relies on techniques involving ionizing …
However, in vivo mapping of BAT activity typically relies on techniques involving ionizing …
Snapshot‐CEST: optimizing spiral‐centric‐reordered gradient echo acquisition for fast and robust 3D CEST MRI at 9.4 T
Gradient echo (GRE)‐based acquisition provides a robust readout method for chemical
exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST …
exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST …
Creatine and phosphocreatine mapping of mouse skeletal muscle by a polynomial and Lorentzian line‐shape fitting CEST method
Purpose To obtain high‐resolution Cr and PCr maps of mouse skeletal muscle using a
polynomial and Lorentzian line‐shape fitting (PLOF) CEST method. Methods Wild‐type mice …
polynomial and Lorentzian line‐shape fitting (PLOF) CEST method. Methods Wild‐type mice …
Whole‐brain amide CEST imaging at 3T with a steady‐state radial MRI acquisition
Purpose To develop a steady‐state saturation with radial readout chemical exchange
saturation transfer (starCEST) for acquiring CEST images at 3 Tesla (T). The polynomial …
saturation transfer (starCEST) for acquiring CEST images at 3 Tesla (T). The polynomial …
Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI
The goal of this study was to develop a molecular biomarker for the detection of protein
aggregation involved in Alzheimer's disease (AD) by exploiting the features of the water …
aggregation involved in Alzheimer's disease (AD) by exploiting the features of the water …
Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues
Chemical exchange saturation transfer (CEST) MRI has become a promising technique to
assay target proteins and metabolites through their exchangeable protons, noninvasively …
assay target proteins and metabolites through their exchangeable protons, noninvasively …
The exchange rate of creatine CEST in mouse brain
Z Zhang, K Wang, S Park, A Li, Y Li… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose To estimate the exchange rate of creatine (Cr) CEST and to evaluate the pH
sensitivity of guanidinium (Guan) CEST in the mouse brain. Methods Polynomial and …
sensitivity of guanidinium (Guan) CEST in the mouse brain. Methods Polynomial and …