[HTML][HTML] Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

J Yang, D Dai, X Zhang, L Teng, L Ma, YW Yang - Theranostics, 2023 - ncbi.nlm.nih.gov
Cancer remains a severe threat to human health. To date, although various therapeutic
methods, including radiotherapy (RT), chemotherapy, chemodynamic therapy (CDT) …

Metal-organic framework nanoshell structures: preparation and biomedical applications

J Tang, C Huang, Y Liu, T Wang, M Yu, H Hao… - Coordination Chemistry …, 2023 - Elsevier
The integration of metal-organic frameworks (MOFs) and nanoshells to construct MOF
nanoshell structures offers promising therapeutic platforms for biomedical applications …

Nanohybrid double network hydrogels based on a platinum nanozyme composite for antimicrobial and diabetic wound healing

Z Zhou, X Mei, K Hu, M Ma, Y Zhang - ACS applied materials & …, 2023 - ACS Publications
Along with hypoxia, severe bacterial infection, and abnormal pH, continuous inflammatory
response hinders diabetic wounds from healing. It leads to the accumulation of large …

A strategy of Fenton reaction cycloacceleration for high‐performance ferroptosis therapy initiated by tumor microenvironment remodeling

L Huang, J Feng, J Zhu, J Yang… - Advanced …, 2023 - Wiley Online Library
The emerging tumor ferroptosis therapy confronts impediments of the tumor
microenvironment (TME) with weak intrinsic acidity, inadequate endogenous H2O2, and a …

Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy

Y Ding, Q Pan, W Gao, Y Pu, K Luo, B He - Biomaterials Science, 2023 - pubs.rsc.org
Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …

A biomimetic nanoreactor for combinational chemo/chemodynamic therapy of choriocarcinoma through synergistic apoptosis and ferroptosis strategy

H Yu, H Zhao, Y Zhang, Y Hou, R Li, T Liang… - Chemical Engineering …, 2023 - Elsevier
Choriocarcinoma is a malignant tumor caused by aberrant proliferation and excessive
invasion of trophoblastic cells in the uterus. Treatment for choriocarcinoma is hampered by …

Copper-olsalazine metal-organic frameworks as a nanocatalyst and epigenetic modulator for efficient inhibition of colorectal cancer growth and metastasis

J Li, Z Zhang, J Li, JE Cun, Q Pan, W Gao, K Luo, B He… - Acta Biomaterialia, 2022 - Elsevier
Despite the extensive explorations of nanoscale metal− organic frameworks (nanoMOFs) in
drug delivery, the intrinsic bioactivity of nanoMOFs, such as anticancer activity, is severely …

[HTML][HTML] Iron oxide nanoparticles (Fe3O4, γ-Fe2O3 and FeO) as photothermal heat mediators in the first, second and third biological windows

AG Roca, JF López-Barbera, A Lafuente, F Özel… - Physics Reports, 2023 - Elsevier
Nanotherapies are gaining increased interest for the treatment diverse diseases, particularly
cancer, since they target the affected area directly, presenting higher efficacy and reduced …

Glutathione-sensitive mesoporous nanoparticles loaded with cinnamaldehyde for chemodynamic and immunological therapy of cancer

L Zhu, W Li, C Liu, S Yue, Y Qiao, Y Cui… - Journal of Materials …, 2023 - pubs.rsc.org
Chemodynamic therapy as a novel type of chemotherapy can damage the DNA structures
and induce cell apoptosis and immunogenic cell death (ICD) through generating reactive …

Photothermal synergistic nitric oxide controlled release injectable self-healing adhesive hydrogel for biofilm eradication and wound healing

W Peng, L Li, Y Zhang, H Su, X Jiang, H Liu… - Journal of Materials …, 2024 - pubs.rsc.org
The development of injectable self-healing adhesive hydrogel dressings with excellent
bactericidal activity and wound healing ability is urgently in demand for combating biofilm …