Despite ongoing vaccination COVID-19 is a global healthcare problem because of the lack
of an effective targeted therapy. In severe COVID-19 manifesting as acute respiratory …

The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …

Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

Simple Summary Children with a COVID-19 infection are at risk of developing a novel
syndrome called multisystem inflammatory syndrome in children (MIS-C). This disease state …

The COVID-19 pandemic caused by the coronavirus 2 of the severe acute respiratory
syndrome (SARS-CoV-2) has significantly affected people around the world, leading to …

Several genetic associations have been identified in individuals with severe COVID-19 and
MIS-C via various genetic approaches. Broadly speaking, COVID-19 genetic associations …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been at the
forefront of health sciences research since its emergence in China in 2019 that quickly led to …

The Coronavirus-19 disease (COVID-19) has claimed over 6.8 million lives since first being
reported in late 2019. The virus that causes COVID-19 disease is highly contagious and …

Identification of transcriptional regulatory mechanisms and signaling networks involved in
the response of host cells to infection by SARS-CoV-2 is a powerful approach that provides …

Abstract Coronavirus disease 2019 (COVID-19) has emerged since December 2019 and
was later characterized as a pandemic by WHO, imposing a major public health threat …