Molecular physiology of water balance

MA Knepper, TH Kwon, S Nielsen - New England Journal of …, 2015 - Mass Medical Soc
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[HTML][HTML] Molecular mechanisms governing aquaporin relocalisation

A Markou, L Unger, M Abir-Awan, A Saadallah… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the
movement of water across biological membrane by osmosis, as well as facilitating the …

Aquaporin 2 regulation: implications for water balance and polycystic kidney diseases

ETB Olesen, RA Fenton - Nature Reviews Nephrology, 2021 - nature.com
Targeting the collecting duct water channel aquaporin 2 (AQP2) to the plasma membrane is
essential for the maintenance of mammalian water homeostasis. The vasopressin V2 …

Nephrogenic diabetes insipidus: essential insights into the molecular background and potential therapies for treatment

HB Moeller, S Rittig, RA Fenton - Endocrine reviews, 2013 - academic.oup.com
The water channel aquaporin-2 (AQP2), expressed in the kidney collecting ducts, plays a
pivotal role in maintaining body water balance. The channel is regulated by the peptide …

Renal aquaporins and water balance disorders

MLA Kortenoeven, RA Fenton - … et Biophysica Acta (BBA)-General Subjects, 2014 - Elsevier
Abstract Background Aquaporins (AQPs) are a family of proteins that can act as water
channels. Regulation of AQPs is critical to osmoregulation and the maintenance of body …

Molecular biology of aquaporins

C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …

Phosphorylation of aquaporin-2 regulates its endocytosis and protein–protein interactions

HB Moeller, J Praetorius… - Proceedings of the …, 2010 - National Acad Sciences
The water channel aquaporin-2 (AQP2) is essential for urine concentration. Vasopressin
regulates phosphorylation of AQP2 at four conserved serine residues at the COOH-terminal …

Vasopressin and the regulation of aquaporin-2

JLL Wilson, CA Miranda, MA Knepper - Clinical and experimental …, 2013 - Springer
Water excretion is regulated in large part through the regulation of osmotic water
permeability of the renal collecting duct epithelium. Water permeability is controlled by …

Aquaporins in kidney pathophysiology

Y Noda, E Sohara, E Ohta, S Sasaki - Nature Reviews Nephrology, 2010 - nature.com
Seven aquaporin water channels are expressed in human kidneys, and they have key roles
in maintaining body water homeostasis. Impairment of their function can result in …

Phosphorylation-dependent regulation of mammalian aquaporins

V Nesverova, S Törnroth-Horsefield - Cells, 2019 - mdpi.com
Water homeostasis is fundamental for cell survival. Transport of water across cellular
membranes is governed by aquaporins—tetrameric integral membrane channels that are …