The rapid proliferation of cancer cells combined with deficient vessels cause regions of
nutrient and O2 deprivation in solid tumors. Some cancer cells can adapt to these extreme …

Development of an anastomotic leak (AL) following intestinal surgery for the treatment of
colorectal cancers is a life-threatening complication. Failure of the anastomosis to heal …

Vascular complications following solid organ transplantation may lead to graft ischemia,
dysfunction or loss. Imaging approaches can provide intermittent assessments of graft …

Continuous, real-time monitoring of perfusion after microsurgical free tissue transfer or solid
organ allotransplantation procedures can facilitate early diagnosis of and intervention for …

Real-time detection of tissue oxygenation in the nervous system is crucial in neuroscience
studies and clinical diagnostics. Complementary to blood oxygenation levels, the partial …

Close monitoring of vital physiological parameters is often key in following the evolution of
certain medical conditions (eg, diabetes, infections, post-operative status or post-traumatic …

The development of wireless implantable sensors and integrated systems, enabled by
advances in flexible and stretchable electronics technologies, is emerging to advance …

Three-dimensional (3D) culture models have gained relevant interest in tissue engineering
and drug discovery owing to their suitability to reproduce in vitro some key aspects of human …

We report herein a Pt (IV) prodrug with metronidazole in axial positions Pt-Mnz. The
nitroaromatic axial ligand was conjugated with a cisplatin scaffold to irreversibly reduce …

The goal of achieving enhanced diagnosis and continuous monitoring of human health has
led to a vibrant, dynamic and well-funded field of research in medical sensing and biosensor …