[HTML][HTML] Nutrition and cancer: a review of the evidence for an anti-cancer diet

MS Donaldson - Nutrition journal, 2004 - Springer
It has been estimated that 30–40 percent of all cancers can be prevented by lifestyle and
dietary measures alone. Obesity, nutrient sparse foods such as concentrated sugars and …

Intravenous vitamin C and cancer: a systematic review

H Fritz, G Flower, L Weeks, K Cooley… - Integrative cancer …, 2014 - journals.sagepub.com
Background. Intravenous vitamin C (IVC) is a contentious adjunctive cancer therapy, widely
used in naturopathic and integrative oncology settings. We conducted a systematic review of …

Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial

F Liu, Y Zhu, J Zhang, Y Li, Z Peng - BMJ open, 2020 - bmjopen.bmj.com
Introduction The rapid worldwide spread of COVID-19 has caused a global health crisis. To
date, symptomatic supportive care has been the most common treatment. It has been …

[HTML][HTML] Effect of high-dose ascorbic acid on vasopressor's requirement in septic shock

MH Zabet, M Mohammadi, M Ramezani… - Journal of research in …, 2016 - journals.lww.com
Objective: Effects of ascorbic acid on hemodynamic parameters of septic shock were
evaluated in nonsurgical critically ill patients in limited previous studies. In this study, the …

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues

Q Chen, MG Espey, MC Krishna… - Proceedings of the …, 2005 - National Acad Sciences
Human pharmacokinetics data indicate that iv ascorbic acid (ascorbate) in pharmacologic
concentrations could have an unanticipated role in cancer treatment. Our goals here were to …

[HTML][HTML] Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of high-dose intravenous ascorbic acid in patients with advanced cancer

CM Stephenson, RD Levin, T Spector… - Cancer chemotherapy and …, 2013 - Springer
Purpose This phase I clinical trial evaluated the safety, tolerability, and pharmacokinetics of
high-dose intravenous (iv) ascorbic acid as a monotherapy in patients with advanced solid …

[HTML][HTML] Phase I clinical trial of iv ascorbic acid in advanced malignancy

LJ Hoffer, M Levine, S Assouline, D Melnychuk… - Annals of …, 2008 - Elsevier
Background Ascorbic acid is a widely used and controversial alternative cancer treatment. In
millimolar concentrations, it is selectively cytotoxic to many cancer cell lines and has in vivo …

[HTML][HTML] High-dose intravenous vitamin C combined with cytotoxic chemotherapy in patients with advanced cancer: a phase I-II clinical trial

LJ Hoffer, L Robitaille, R Zakarian, D Melnychuk… - PloS one, 2015 - journals.plos.org
Background Biological and some clinical evidence suggest that high-dose intravenous
vitamin C (IVC) could increase the effectiveness of cancer chemotherapy. IVC is widely used …

[HTML][HTML] Systematic review of intravenous ascorbate in cancer clinical trials

G Nauman, JC Gray, R Parkinson, M Levine, CJ Paller - Antioxidants, 2018 - mdpi.com
Background: Ascorbate (vitamin C) has been evaluated as a potential treatment for cancer
as an independent agent and in combination with standard chemotherapies. This review …

High-dose vitamin C (ascorbic acid) therapy in the treatment of patients with advanced cancer

S Ohno, Y Ohno, N Suzuki, GI Soma… - Anticancer research, 2009 - ar.iiarjournals.org
Vitamin C (ascorbic acid, ascorbate) has a controversial history in cancer treatment.
Emerging evidence indicates that ascorbate in cancer treatment deserves re-examination …