Leukemia inhibitory factor: an important cytokine in pathologies and cancer

MM Jorgensen, P de la Puente - Biomolecules, 2022 - mdpi.com
Leukemia Inhibitory Factor (LIF) is a member of the IL-6 cytokine family and is expressed in
almost every tissue type within the body. Although LIF was named for its ability to induce …

In-situ monitoring of xenobiotics using genetically engineered whole-cell-based microbial biosensors: recent advances and outlook

SA Ali, D Mittal, G Kaur - World Journal of Microbiology and Biotechnology, 2021 - Springer
Industrialisation, directly or indirectly, exposes humans to various xenobiotics. The
increased magnitude of chemical pesticides and toxic heavy metals in the environment, as …

Leukaemia inhibitory factor (LIF) inhibits cancer stem cells tumorigenic properties through hippo kinases activation in gastric cancer

L Seeneevassen, J Giraud, S Molina-Castro, E Sifré… - Cancers, 2020 - mdpi.com
Cancer stem cells (CSCs) present chemo-resistance mechanisms contributing to tumour
maintenance and recurrence, making their targeting of utmost importance in gastric cancer …

Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening into the molecular mechanism of …

V Karri, D Ramos, JB Martinez, A Odena, E Oliveira… - Journal of …, 2018 - Elsevier
Chronic exposure to heavy metals such as Pb, As, and MeHg can be associated with an
increased risk of developing neurodegenerative diseases. Our in vitro bioassays results …

High-Resolution Mass Spectrometer–Based Ultra-Deep Profile of Milk Whey Proteome in Indian Zebu (Sahiwal) Cattle

A Chopra, SA Ali, S Bathla, P Rawat, V Vohra… - Frontiers in …, 2020 - frontiersin.org
Milk serves as a mode of protection to neonate through transferring the host defense
proteins from mother to offspring. It also guards the mammary gland against various types of …

CRISPR-Cas9 based knockout of S100A8 in mammary epithelial cells enhances cell proliferation and triggers oncogenic transformation via the PI3K-Akt pathway …

P Singh, SA Ali, S Kumar, AK Mohanty - Journal of Proteomics, 2023 - Elsevier
S100A8 is a calcium-binding protein with multiple functions, including being a
chemoattractant for phagocytes and playing a key role in the inflammatory response. Its …

Protein glycosylation: bridging maternal–fetal crosstalk during embryo implantation

X Sun, Y Feng, Q Ma, Y Wang, F Ma - Biology of Reproduction, 2023 - academic.oup.com
Infertility is a challenging health problem that affects 8–15% of couples worldwide.
Establishing pregnancy requires successful embryo implantation, but about 85% of …

[HTML][HTML] AMPK/SIRT1 signaling through p38MAPK mediates Interleukin-6 induced neuroendocrine differentiation of LNCaP prostate cancer cells

S Natani, VM Dhople, A Parveen, KK Sruthi… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Neuroendocrine Prostate Cancer (NEPC) is an aggressive form of androgen
independent prostate cancer (AIPC), correlated with therapeutic resistance. Interleukin (IL)-6 …

Peptide profiling in cow urine reveals molecular signature of physiology-driven pathways and in-silico predicted bioactive properties

R Kumar, SA Ali, SK Singh, V Bhushan, JK Kaushik… - Scientific reports, 2021 - nature.com
Peptidomics allows the identification of peptides that are derived from proteins. Urinary
peptidomics has revolutionized the field of diagnostics as the samples represent complete …

Leukaemia inhibitory factor in gastric cancer: friend or foe?

L Seeneevassen, OCB Martin, P Lehours, P Dubus… - Gastric Cancer, 2022 - Springer
IL-6 family cytokine leukaemia inhibitory factor (LIF) study has deciphered a variety of
effects, in physiology as well as pathology. Despite the sudden arousal in LIF interest in …