Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application

BG Carvalho, BT Ceccato, M Michelon, SW Han… - Pharmaceutics, 2022 - mdpi.com
Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …

Ultra-small lipid nanoparticles encapsulating sorafenib and midkine-siRNA selectively-eradicate sorafenib-resistant hepatocellular carcinoma in vivo

MA Younis, IA Khalil, YHA Elewa, Y Kon… - Journal of Controlled …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is a fatal disease with limited therapeutic choices. The
stroma-rich tumor microenvironment hinders the in vivo delivery of most nanomedicines …

Targeted drug delivery systems for curcumin in breast cancer therapy

M Huang, BT Zhai, Y Fan, J Sun, YJ Shi… - International Journal …, 2023 - Taylor & Francis
Breast cancer (BC) is the most prevalent type of cancer in the world and the main reason
women die from cancer. Due to the significant side effects of conventional treatments such …

Robotics, microfluidics, nanotechnology and AI in the synthesis and evaluation of liposomes and polymeric drug delivery systems

E Egorov, C Pieters, H Korach-Rechtman… - Drug Delivery and …, 2021 - Springer
The field of nanotechnology and personalised medicine is undergoing drastic changes in
the approach and efficiency of experimentation. The COVID-19 pandemic has spiralled into …

Antitumoral activities of curcumin and recent advances to improve its oral bioavailability

MC Nocito, A De Luca, F Prestia, P Avena, D La Padula… - Biomedicines, 2021 - mdpi.com
Curcumin, a main bioactive component of the Curcuma longa L. rhizome, is a phenolic
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …

Liposomes as multifunctional nano-carriers for medicinal natural products

X Cheng, H Yan, S Pang, M Ya, F Qiu, P Qin… - Frontiers in …, 2022 - frontiersin.org
Although medicinal natural products and their derivatives have shown promising effects in
disease therapies, they usually suffer the drawbacks in low solubility and stability in the …

Microfluidic-mediated nano-drug delivery systems: from fundamentals to fabrication for advanced therapeutic applications

Q Ma, J Cao, Y Gao, S Han, Y Liang, T Zhang, X Wang… - Nanoscale, 2020 - pubs.rsc.org
Nano-drug delivery systems (NDDS) are functional drug-loaded nanocarriers extensively
applied in the healthcare and pharmaceutical areas. Recently, microfluidics has been …

Manufacturing of 3D-printed microfluidic devices for the synthesis of drug-loaded liposomal formulations

G Ballacchino, E Weaver, E Mathew, R Dorati… - International Journal of …, 2021 - mdpi.com
Microfluidic technique has emerged as a promising tool for the production of stable and
monodispersed nanoparticles (NPs). In particular, this work focuses on liposome production …

Microfluidic manufacture of lipid-based nanomedicines

K Osouli-Bostanabad, S Puliga, DR Serrano, A Bucchi… - Pharmaceutics, 2022 - mdpi.com
Nanoparticulate technologies have revolutionized drug delivery allowing for passive and
active targeting, altered biodistribution, controlled drug release (temporospatial or triggered) …