Transposable elements shape the evolution of mammalian development
AD Senft, TS Macfarlan - Nature Reviews Genetics, 2021 - nature.com
Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …
methylation has numerous functions: it is implicated in the repression of transposons and …
Regulation of transposable elements by DNA modifications
Maintenance of genome stability requires control over the expression of transposable
elements (TEs), whose activity can have substantial deleterious effects on the host …
elements (TEs), whose activity can have substantial deleterious effects on the host …
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals
DNA methylation is essential to development and cellular physiology in mammals. Faulty
DNA methylation is frequently observed in human diseases like cancer and neurological …
DNA methylation is frequently observed in human diseases like cancer and neurological …
Mammalian DNA methyltransferases: new discoveries and open questions
As part of the epigenetic network, DNA methylation is a major regulator of chromatin
structure and function. In mammals, it mainly occurs at palindromic CpG sites, but …
structure and function. In mammals, it mainly occurs at palindromic CpG sites, but …
Evolution of DNA methylome diversity in eukaryotes
Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …
[HTML][HTML] DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation
S Adam, H Anteneh, M Hornisch, V Wagner… - Nature …, 2020 - nature.com
DNA methylation maintenance by DNMT1 is an essential process in mammals but molecular
mechanisms connecting DNA methylation patterns and enzyme activity remain elusive …
mechanisms connecting DNA methylation patterns and enzyme activity remain elusive …
Diversity of cytosine methylation across the fungal tree of life
AJ Bewick, BT Hofmeister, RA Powers… - Nature ecology & …, 2019 - nature.com
The generation of thousands of fungal genomes is leading to a better understanding of
genes and genomic organization within the kingdom. However, the epigenome, which …
genes and genomic organization within the kingdom. However, the epigenome, which …
The role of epigenetics in allergy and asthma development
BA Alhamwe, F Alhamdan, A Ruhl… - Current opinion in …, 2020 - journals.lww.com
The role of epigenetics in allergy and asthma development : Current Opinion in Allergy and
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …
Clinical Immunology The role of epigenetics in allergy and asthma development : Current …
[HTML][HTML] Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
Cytosine methylation is an ancient epigenetic modification yet its function and extent within
genomes is highly variable across eukaryotes. In mammals, methylation controls …
genomes is highly variable across eukaryotes. In mammals, methylation controls …