Purpose Microsatellites are widely distributed repetitive DNA motifs, accounting for
approximately 3% of the genome. Due to mismatch repair system deficiency, insertion or …

Endometrial carcinoma is the most common cancer of the female genital tract. This review
article discusses the usefulness of molecular techniques to classify endometrial carcinoma …

Endometrial disorders represent a major gynaecological burden. Current research models
fail to recapitulate the nature and heterogeneity of these diseases, thereby hampering …

Accurate duplication of DNA prior to cell division is essential to suppress mutagenesis and
tumour development. The high fidelity of eukaryotic DNA replication is due to a combination …

Identifying putative biomarkers of clinical outcomes in cancer is crucial for successful
enrichment, and for the selection of patients who are the most likely to benefit from a specific …

Tamoxifen has been prescribed to millions of females for breast cancer prevention or
treatment. However, tamoxifen is known to significantly enhance the risk of developing …

Endometrial cancer (EC) is the most common gynaecologic malignancy in the developed
countries. Recent evidence suggests that histopathological subtyping together with …

Objectives The tumor microenvironment (TME) play important roles in progression of
endometrial carcinoma (EC). We aimed to assess the cell populations in TME of EC …

The treatment for endometrial cancer is rapidly evolving with the development of molecular
analysis and novel strategies. Surgical resection, cytotoxic chemotherapy, endocrine or …

Background Growth arrest-specific 5 (GAS5) was reported to be implicated and aberrantly
express in multiple cancers. However, the expression and mechanism of action of GAS5 …