In this paper we review the problems of antibiotic resistance in community acquired
infections. We discuss pathogens that have a large impact on morbidity and mortality in the …

Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis, and
acute otitis media in children and adults worldwide. In the age group of< 2 years the …

Background. Operating on the principle that most acute otitis media (AOM) episodes resolve
without antibiotics, doctors in the Netherlands usually manage AOM in children with initial …

Background. The prevalence of multiantimicrobial resistance among Streptococcus
pneumoniae continues to increase worldwide. In patients presenting with infection possibly …

Objective: To determine the effect of antibiotic treatment for acute otitis media in children
between 6 months and 2 years of age. Design: Practice based, double blind, randomised …

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available
antibiotics, and requires new approaches to antibiotic discovery and development …

A multicenter study was done during 1993–1995 to investigate prospectively the influence of
several prognostic factors for predicting the risk of death among patients with pneumococcal …

Nasopharyngeal carriage of Haemophilus influenzae, Streptococcus pneumoniae, and
Moraxella catarrhalis was studied in 259 children attending day care centers (DCC) in …

Abstract In a 10-year period, 1987–1997, there was a> 4-fold increase in the rate of
pneumococcal bacteremia in Sweden. Invasive pneumococcal isolates (n= 1136), which …

In a nationwide study in Germany covering 13 clinical microbiology laboratories, a total of
307 Streptococcus pyogenes (mainly pharyngitis) and 333 Streptococcus pneumoniae …