The increasing prevalence of antibiotic resistance is a threat to human health, particularly within vulnerable populations in the hospital and acute care settings. This leads to …
V Trebosc, S Gartenmann, M Tötzl, V Lucchini… - MBio, 2019 - Am Soc Microbiol
Nosocomial infections with Acinetobacter baumannii are a global problem in intensive care units with high mortality rates. Increasing resistance to first-and second-line antibiotics has …
C Barbosa, V Trebosc, C Kemmer… - Molecular biology …, 2017 - academic.oup.com
When bacteria evolve resistance against a particular antibiotic, they may simultaneously gain increased sensitivity against a second one. Such collateral sensitivity may be exploited …
A Górski, R Międzybrodzki, M Łobocka… - Viruses, 2018 - mdpi.com
In this article we explain how current events in the field of phage therapy may positively influence its future development. We discuss the shift in position of the authorities …
What is known and objective Acinetobacter baumannii is one of the most important nosocomial pathogens with the ability to cause infections such as meningitis, pneumonia …
Evolution is at the core of the impending antibiotic crisis. Sustainable therapy must thus account for the adaptive potential of pathogens. One option is to exploit evolutionary trade …
B Luna, V Trebosc, B Lee, M Bakowski, A Ulhaq… - Nature …, 2020 - nature.com
Industry screens of large chemical libraries have traditionally relied on rich media to ensure rapid bacterial growth in high-throughput testing. We used eukaryotic, nutrient-limited growth …
JC McGuffey, CD Jackson-Litteken, G Di Venanzio… - Mbio, 2023 - Am Soc Microbiol
Successful pathogens must be able to adapt to a multitude of stressors imposed by their host. Acinetobacter baumannii has emerged as a major global health threat due to its …
Background Efflux pumps mediate antimicrobial resistance in several WHO critical priority bacterial pathogens. However, most available data come from laboratory strains. The …