Metathesis in the synthesis of aromatic compounds

WAL van Otterlo, CB De Koning - Chemical reviews, 2009 - ACS Publications
The importance of aromatic structures in organic chemistry can never be underestimated.
Nature uses compounds containing aromatic or heteroaromatic nuclei extensively as the …

Muscarine, imidazole, oxazole and thiazole alkaloids

Z Jin - Natural Product Reports, 2009 - pubs.rsc.org
Covering: July 2005 to June 2007. Previous review: Nat. Prod. Rep., 2006, 23, 464–496.
Nature abounds with a great number of natural products containing five-membered …

Terpenyl-purines from the sea

M Gordaliza - Marine Drugs, 2009 - mdpi.com
Agelasines, asmarines and related compounds are natural products with a hybrid terpene-
purine structure isolated from numerous genera of sponges (Agela sp., Raspailia sp.). Some …

Nitrosopurines en route to potently cytotoxic asmarines

KK Wan, K Iwasaki, JC Umotoy, DW Wolan… - Angewandte …, 2015 - Wiley Online Library
A nitrosopurine ene reaction easily assembles the asmarine pharmacophore and transmits
remote stereochemistry to the diazepine‐purine hetereocycle. This reaction generates …

Synthesis of complex fused polycyclic heterocycles utilizing IMDAF reactions of allylamino-or allyloxy-furyl (hetero) arenes

ML Read, A Krapp, PO Miranda, LL Gundersen - Tetrahedron, 2012 - Elsevier
Arenes and heteroarenes carrying a halogen and an amino-or hydroxy group have been
converted to allylamino-or allyloxy-furyl-(hetero) arenes. These compounds underwent …

Synthesis of unsaturated 1, 4-heteroatom-containing benzo-fused heterocycles using a sequential isomerization–ring-closing metathesis strategy

GL Morgans, EL Ngidi, LG Madeley, SD Khanye… - Tetrahedron, 2009 - Elsevier
A small library of 1, 4-benzodioxins and 4H-1, 4-benzoxazines was synthesized from the
corresponding bis-allyloxy precursors by way of an initial isomerization to the bis-vinyloxy …

Marine alkylpurines: A promising group of bioactive marine natural products

PA García, E Valles, D Díez, MÁ Castro - Marine Drugs, 2018 - mdpi.com
Marine secondary metabolites with a purine motif in their structure are presented in this
review. The alkylpurines are grouped according to the size of the alkyl substituents and their …

Conjuring a supernatural product–DelMarine

KK Wan, RA Shenvi - Synlett, 2016 - thieme-connect.com
The asmarine alkaloids constitute a small family of terpene-nucleobase marine metabolites
defined by a unique N-hydroxy-diazepine pharmacophore that effects moderate to potent …

[图书][B] Organic Reactions, Volume 100

SE Denmark - 2019 - books.google.com
Written by a" who is who" of leading organic chemists, this anniversary volume represent the
Organic Reactions editors' choice of the most important, ground-breaking and versatile …

Synthesis of Substituted 2,3‐Dihydro‐1H‐2‐benzazepines and 1,2‐Dihydroisoquinolines Using an Isomerization‐Ring‐Closing Metathesis Strategy: Scope and …

JL Panayides, R Pathak, CB de Koning… - 2007 - Wiley Online Library
An isomerization‐ring‐closing metathesis (RCM) approach was used for the synthesis of
substituted 2, 3‐dihydro‐1H‐2‐benzazepines and 1, 2‐dihydroisoquinolines. The 2, 3 …