[HTML][HTML] Investigation of some plant stilbenoids and their fragments for the identification of inhibitors of SARS-CoV-2 viral spike/ACE2 protein binding
In silico binding studies were conducted on the known plant-derived polyphenolic tetrameric
stilbenoids,(–)-hopeaphenol (1), vaticanol B (2) and vatalbinoside A (3) and their monomeric …
stilbenoids,(–)-hopeaphenol (1), vaticanol B (2) and vatalbinoside A (3) and their monomeric …
Computational discovery of dual potential inhibitors of SARS‐CoV‐2 spike/ACE2 and Mpro: 3D-pharmacophore, docking-based virtual screening, quantum …
BD Bekono, PA Onguéné, CV Simoben… - European Biophysics …, 2024 - Springer
To find drugs against COVID-19, caused by the SARS-CoV-2, promising targets include the
fusion of the viral spike with the human angiotensin-converting enzyme 2 (ACE2) as well as …
fusion of the viral spike with the human angiotensin-converting enzyme 2 (ACE2) as well as …
Design, isolation, synthesis, and mechanistic insight of flavonoids isolated from Beilschmiedia obscura, as potential α-glucosidase inhibitors
SL Nyemeck, KO Eyong, R Bidingha… - Phytochemistry …, 2024 - Elsevier
Flavonoids based on the flavone 1–3 and a biflavanoid 4 with a flavan nucleus were
isolated from Beilschmiedia obscura (Stapf). These compounds which include 5-hydroxy-7 …
isolated from Beilschmiedia obscura (Stapf). These compounds which include 5-hydroxy-7 …
[HTML][HTML] Computer-aided design, synthesis, and biological evaluation of 4-chloro-N-(2-oxo-3-(2-pyridin-4-yl) hydrazineylidene) indolin-5yl) benzamide and 1-(4 …
The emergence of the severe acute respiratory syndrome 2 (SARS-CoV-2) as a global threat
has driven the urgent need for the identification of bioactive molecules capable of controlling …
has driven the urgent need for the identification of bioactive molecules capable of controlling …
Insight of Natural Compounds Halimane Diterpenoids against Mycobacterium tuberculosis: Virtual Screening, DFT, Drug-Likeness, and Molecular Dynamics …
LGE Andiga, BD Bekono, DM Bikele… - Computational …, 2024 - archive.jibiology.com
In the purpose to design novel antituberculosis (anti-TB) drugs agents against
Mycobacterium tuberculosis (Mtb), we have built a molecular library around 42 Halimane …
Mycobacterium tuberculosis (Mtb), we have built a molecular library around 42 Halimane …
Effects of some anti-ulcer and anti-inflammatory natural products on cyclooxygenase and lipoxygenase enzymes: insights from in silico analysis
Gastric and duodenal ulcers are increasingly becoming global health burdens. The side
effects of conventional treatments such as non-steroid anti-inflammatory drugs (NSAIDs) …
effects of conventional treatments such as non-steroid anti-inflammatory drugs (NSAIDs) …
[PDF][PDF] The Microbe
In silico binding studies were conducted on the known plant-derived polyphenolic tetrameric
stilbenoids,(–)-hopeaphenol (1), vaticanol B (2) and vatalbinoside A (3) and their monomeric …
stilbenoids,(–)-hopeaphenol (1), vaticanol B (2) and vatalbinoside A (3) and their monomeric …
[PDF][PDF] The Microbe
The emergence of the severe acute respiratory syndrome 2 (SARS-CoV-2) as a global threat
has driven the urgent need for the identification of bioactive molecules capable of controlling …
has driven the urgent need for the identification of bioactive molecules capable of controlling …