The tumor microenvironment (TME) is a complex and ever-changing “rogue organ”
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …

In recent years, gene therapy based on miRNA has been employed as a potential growing
technique for treating various co-morbidities. Direct administration of miRNA is unrealistic …

Many infections and stress signals can rapidly activate the NLRP3 inflammasome to elicit
robust inflammatory responses. This activation requires a priming step, which is thought to …

Glioma is the most common malignant tumor in the central nervous system. Altered long
noncoding RNAs (lncRNAs) are playing regulatory roles in physiological and pathogenic …

The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

Our understanding of how cells communicate has undergone a paradigm shift since the
recent recognition of the role of exosomes in intercellular signaling. In this study, we …

Background Acting as inflammatory mediators, tumor oncogenes or suppressors,
microRNAs are involved in cell survival, death, epithelial–mesenchymal transition and …

Abstract Background Long non-coding RNAs (LncRNAs) are closely related to the
occurrence of cancer, but its mechanism in gastric cancer (GC) is still largely unclear. Aims …

Tumor-associated macrophages are a critical component of tumor microenvironments,
which affect tumor growth, tumor angiogenesis, immune suppression, metastasis and …

Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. It
has been estimated that more than one‐third of patients are diagnosed when CRC has …