I Vanni, ET Tanda, F Spagnolo, V Andreotti… - Frontiers in Molecular …, 2020 - frontiersin.org
The incidence of melanoma, among the most lethal cancers, is widespread and increasing. Metastatic melanoma has a poor prognosis, representing about 90% of skin cancer …
P Meng, B Koopman, K Kok, A Ter Elst, E Schuuring… - Lung Cancer, 2020 - Elsevier
Introduction Previous studies have reported an acquiredBRAF V600E mutation as a potential resistance mechanism to osimertinib treatment in advanced NSCLC patients with …
RH Kim, S Nomikou, N Coudray, G Jour, Z Dawood… - BioRxiv, 2019 - biorxiv.org
Image-based analysis as a rapid method for mutation detection can be advantageous in research or clinical settings when tumor tissue is limited or unavailable for direct testing …
M Kwak, NE Farrow, AKS Salama… - Journal of surgical …, 2019 - Wiley Online Library
There has been a rapid increase in adjuvant therapies approved for treatment following surgical resection of stages III/IV melanoma. We review current indications for adjuvant …
Purpose Evaluation of genetic mutations in cancers is important because distinct mutational profiles help determine individualized drug therapy. However, molecular analyses are not …
JD Goldsmith, ML Troxell… - … of pathology & …, 2024 - meridian.allenpress.com
Context.—In 2014, the College of American Pathologists developed an evidence-based guideline to address analytic validation of immunohistochemical assays. Fourteen …
M Van Haele, S Vander Borght, A Ceulemans… - Journal of clinical …, 2020 - jcp.bmj.com
Aims Precision medicine therapy is remodelling the diagnostic landscape of cancer. The success of these new therapies is often based on the presence or absence of a specific …
A Uguen, G Troncone - Journal of Clinical Pathology, 2018 - jcp.bmj.com
Methods The MEDLINE and Google Scholar databases were searched to retrieve studies addressing the Idylla system performance compared with other diagnostic methods. Only …
H Huang, S Springborn, K Haug, K Bartow… - The Journal of Molecular …, 2019 - Elsevier
The Idylla Mutation Test System is an automated, PCR-based mutation testing system. The advantages of this system can greatly impact the delivery of precision medicine. We …