The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Ruthenium complex is an important compound group for antitumor drug research and
development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered …

Melanoma is the most aggressive form of skin cancer and its annual incidence rates are
increasing globally. Though chemotherapy, radiotherapy, immunotherapy and targeted …

The DNA-alkylating derivative chlorambucil was coordinated in the axial position to atypical
cytotoxic, heterocyclic, and non-DNA coordinating platinum (IV) complexes of type,[PtIV …

This review focuses on light-activated ruthenium anticancer compounds and the factors that
influence which pathway is favored. Photodynamic therapy (PDT) is favored by π expansion …

Photoactivated chemotherapy (PACT) is a form of target-oriented cancer therapy that
exploits light of the proper wavelength to selectively activate the drug. Among the prodrugs …

A new series of cytotoxic platinum (IV) complexes (1–8) incorporating halogenated
phenylacetic acid derivatives (4-chlorophenylacetic acid, 4-fluorophenylacetic acid, 4 …

Chlorambucil-platinum (IV) prodrugs exhibit multi-mechanistic chemotherapeutic activity
with promising anticancer potential. The platinum (II) precursors of the prodrugs have been …

Simple Summary Conventional intravenous platinum (II) chemotherapy medications,
including carboplatin, oxaliplatin and cisplatin, have demonstrated remarkable efficacy in …

This paper uses a unique dataset from Lebanon, a developing country with unstable political
conditions, to explore the drivers of research outcomes. We use the Negative Binomial …