[HTML][HTML] West Nile virus and its emergence in the United States of America

KO Murray, E Mertens, P Desprès - Veterinary research, 2010 - ncbi.nlm.nih.gov
Abstract Zoonotic West Nile virus (WNV) circulates in natural transmission cycles involving
certain mosquitoes and birds, horses, humans, and a range of other vertebrates are …

[PDF][PDF] Pathogenesis and pathophysiology of yellow fever

TP Monath, ADT Barrett - Advances in virus research, 2003 - researchgate.net
E. Heart F. Blood Vessels and Endothelium VI. Pathogenesis and Pathophysiology in the
Intact Host A. Experimental Animal Models B. Spread of Virus within the Host C. Fever and …

Dendritic‐cell‐specific ICAM3‐grabbing non‐integrin is essential for the productive infection of human dendritic cells by mosquito‐cell‐derived dengue viruses

E Navarro‐Sanchez, R Altmeyer, A Amara… - EMBO …, 2003 - embopress.org
Dengue virus (DV) is a mosquito‐borne flavivirus that causes haemorrhagic fever in
humans. DV primarily targets immature dendritic cells (DCs) after a bite by an infected …

[HTML][HTML] The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses

A Sharma, X Zhang, W Dejnirattisai, X Dai, D Gong… - Cell, 2021 - cell.com
The human monoclonal antibody C10 exhibits extraordinary cross-reactivity, potently
neutralizing Zika virus (ZIKV) and the four serotypes of dengue virus (DENV1–DENV4). Here …

Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion

CL Medin, KA Fitzgerald, AL Rothman - Journal of virology, 2005 - Am Soc Microbiol
Elevated circulating levels of chemokines have been reported in patients with dengue fever
and are proposed to contribute to the pathogenesis of dengue disease. To establish in vitro …

Pathogenesis of flavivirus encephalitis

TJ Chambers, MS Diamond - Advances in virus research, 2004 - pmc.ncbi.nlm.nih.gov
Publisher Summary Within the flavivirus family, viruses that cause natural infections of the
central nervous system (CNS) principally include members of the Japanese encephalitis …

Glycoprotein of nonpathogenic rabies viruses is a key determinant of human cell apoptosis

C Préhaud, S Lay, B Dietzschold, M Lafon - Journal of virology, 2003 - Am Soc Microbiol
We showed that, unlike pathogenic rabies virus (RV) strain CVS, attenuated RV strain ERA
triggers the caspase-dependent apoptosis of human cells. Furthermore, we observed that …

Single mutation in the flavivirus envelope protein hinge region increases neurovirulence for mice and monkeys but decreases viscerotropism for monkeys: relevance …

TP Monath, J Arroyo, I Levenbook, ZX Zhang… - Journal of …, 2002 - Am Soc Microbiol
ABSTRACT A chimeric yellow fever (YF) virus/Japanese encephalitis (JE) virus vaccine
(ChimeriVax-JE) was constructed by insertion of the prM-E genes from the attenuated JE …

[HTML][HTML] West Nile virus-induced bax-dependent apoptosis

M del Carmen Parquet, A Kumatori, F Hasebe, K Morita… - FEBS letters, 2001 - Elsevier
The mechanism of cell death induced by West Nile virus (WNV), a causative agent of human
febrile syndrome and encephalitis, was investigated. WNV-infected K562 and Neuro-2a …

[HTML][HTML] Host cell killing by the West Nile Virus NS2B–NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway

MP Ramanathan, JA Chambers, P Pankhong… - Virology, 2006 - Elsevier
The West Nile Virus (WNV) non-structural proteins 2B and 3 (NS2B–NS3) constitute the
proteolytic complex that mediates the cleavage and processing of the viral polyprotein. NS3 …