Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer

A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …

Polygenic risk prediction models for colorectal cancer: a systematic review

M Sassano, M Mariani, G Quaranta, R Pastorino… - BMC cancer, 2022 - Springer
Background Risk prediction models incorporating single nucleotide polymorphisms (SNPs)
could lead to individualized prevention of colorectal cancer (CRC). However, the added …

[HTML][HTML] Prospective evaluation of dietary and lifestyle pattern indices with risk of colorectal cancer in a cohort of younger women

Y Yue, J Hur, Y Cao, FK Tabung, M Wang, K Wu… - Annals of …, 2021 - Elsevier
Background Although colorectal cancer (CRC) incidence in the USA is declining overall, its
incidence is increasing among those younger than 50 years of age. The reasons underlying …

Influence of the duration of type 2 diabetes mellitus on colorectal cancer outcomes

M Herold, AM Szasz, G Szentmartoni, E Martinek… - Scientific Reports, 2023 - nature.com
Type 2 diabetes mellitus (T2DM) is a progressive disease, which affects colorectal cancer
(CRC) survival. However, data on the relationship between CRC survival and T2DM …

Survival of colorectal cancer patients with diabetes mellitus: a meta-analysis

F Petrelli, M Ghidini, E Rausa, A Ghidini… - Canadian Journal of …, 2021 - Elsevier
Objectives Diabetes mellitus (DM) is associated with an elevated risk of various cancers,
including colorectal cancer (CRC). Similarly, pre-existing DM may also influence prognosis …

Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression

Y Shi, L Liu, T Hamada, JA Nowak, M Giannakis… - … Biomarkers & Prevention, 2020 - AACR
Background: We hypothesized that the risk of colorectal cancer in night-shift workers might
be different according to insulin receptor substrate status. Methods: Among 77,470 eligible …

Adipose tissue-associated cancer risk: Is it the fat around the liver, or the fat inside the liver?

G Marchesini, ML Petroni… - Journal of …, 2019 - journal-of-hepatology.eu
The association between obesity and cancer risk has been extensively characterized. In a
prospective study of more than 900,000 adults free of cancer at enrollment and observed …

Type 2 diabetes, glycaemic traits and upper gastrointestinal cancer risk: a prospective cohort study

L Cao, T Wang, H Li, F El Hafa, X Zhu, Y Yu… - J Epidemiol …, 2024 - jech.bmj.com
Background Type 2 diabetes (T2D) has been linked with site-specific upper gastrointestinal
(UGI) cancers during the past decades, but associations are still inconclusive. This study …

Discovery and validation of PZP as a novel serum biomarker for screening lung adenocarcinoma in type 2 diabetes mellitus patients

J Yang, C Yang, H Shen, W Wu, Z Tian, Q Xu… - Cancer Cell …, 2021 - Springer
Background Patients with type 2 diabetes mellitus (T2DM) have an increased risk of
suffering from various malignancies. This study aimed to identify specific biomarkers that can …

Landscape of unconventional γδ T cell subsets in cancer

P Azimnasab-Sorkhabi, M Soltani-Asl… - Molecular Biology …, 2024 - Springer
T cells are broadly categorized into two groups, namely conventional and unconventional T
cells. Conventional T cells are the most prevalent and well-studied subset of T cells. On the …