Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …

Despite significant advances in standard of care therapies, the 5-year survival rate for
metastatic colorectal cancer (CRC) remains around 12%. Immunotherapy has not provided …

Background Immunotherapy focuses on selectively enhancing the host's immune response
against malignant disease. It has been investigated as an important treatment modality …

Many new therapies are currently being used to treat cancer. Among these new methods,
chemotherapy based on peptides has been of great interest due to the unique advantages …

CEP55 was initially identified as a pivotal component of abscission, the final stage of
cytokinesis, serving to regulate the physical separation of two daughter cells. Over the past …

Cancer stem-like cells (CSCs) and tumor-initiating cells (TICs) are a small population of
cancer cells that share three properties: tumor initiating ability, self-renewal, and …

The centrosomal protein, CEP 55, is a key regulator of cytokinesis, and its overexpression is
linked to genomic instability, a hallmark of cancer. However, the mechanism by which it …

Abstract Background The Cancer/Testis Antigens (CTAs) are an important group of proteins
that are typically restricted to the testis in the normal adult but are aberrantly expressed in …

Cancer vaccines are usually derived from the patient's tumor cells or the antigens found on
their surface, which may help the immune system to identify and kill these malignant cells …

Nanotherapy has emerged as an improved anticancer therapeutic strategy to circumvent the
harmful side effects of chemotherapy. It has been proven to be beneficial to offer multiple …