Alzheimer's disease (AD) is the most common cause of dementia worldwide and is
characterised pathologically by the accumulation of amyloid beta and tau protein …

The recent commercialisation of the first disease-modifying drugs for Alzheimer's disease
emphasises the need for consensus recommendations on the rational use of biomarkers to …

This article focuses on clinical applications of arterial spin labeling (ASL) and is part of a
wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) …

Arterial spin labeled (ASL) magnetic resonance imaging (MRI) is the primary method for
noninvasively measuring regional brain perfusion in humans. We introduce ASLPrep, a …

Importance Meta-analyses of randomized clinical trials have indicated that improved
hypertension control reduces the risk for cognitive impairment and dementia. However, it is …

Importance Antihypertensive treatments benefit cerebrovascular health and cognitive
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …

Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly, affecting millions of people worldwide and clinically characterized by a progressive …

Arterial spin labeling (ASL) magnetic resonance imaging (MRI) has become a popular
approach for studying cerebral hemodynamics in a range of disorders and has recently …

The neuroimaging method of multimodal magnetic resonance imaging (MRI) can identify the
changes in brain structure and function caused by Alzheimer's disease (AD) at different …

Cerebral microvascular rarefaction, the reduction in number of functional or structural small
blood vessels in the brain, is thought to play an important role in the early stages of …