Therapeutic targeting of long non-coding RNAs in cancer
Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …
Clinical utility of circulating non-coding RNAs—an update
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
The long noncoding RNA Malat1: Its physiological and pathophysiological functions
Recent studies suggest that in humans, DNA sequences responsible for protein coding
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …
Risk SNP-mediated promoter-enhancer switching drives prostate cancer through lncRNA PCAT19
The prostate cancer (PCa) risk-associated SNP rs11672691 is positively associated with
aggressive disease at diagnosis. We showed that rs11672691 maps to the promoter of a …
aggressive disease at diagnosis. We showed that rs11672691 maps to the promoter of a …
Noncoding RNA s in disease
E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …
processes. In parallel, a rapidly growing number of studies has unravelled associations …
MALAT1 Long Non-Coding RNA: Functional Implications
The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …
LncRNAs in breast cancer: a link to future approaches
Breast cancer affects millions of women each year. Despite recent advances in targeted
treatments breast cancer remains a significant threat to women's health. In recent years the …
treatments breast cancer remains a significant threat to women's health. In recent years the …
Long noncoding RNAs as novel biomarkers have a promising future in cancer diagnostics
T Shi, G Gao, Y Cao - Disease markers, 2016 - Wiley Online Library
Cancers have a high mortality rate due to lack of suitable specific early diagnosis tumor
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …
biomarkers. Emerging evidence is accumulating that lncRNAs (long noncoding RNAs) are …
Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma cells
X Wang, M Li, Z Wang, S Han, X Tang, Y Ge… - Journal of biological …, 2015 - ASBMB
MALAT1, a highly conserved long noncoding RNA, is deregulated in several types of
cancers. However, its role in esophageal squamous cell carcinoma (ESCC) and its …
cancers. However, its role in esophageal squamous cell carcinoma (ESCC) and its …
[HTML][HTML] Regulation of lncRNA and its role in cancer metastasis
J Li, H Meng, Y Bai, K Wang - Oncology research, 2016 - ncbi.nlm.nih.gov
Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …
process by which cancer spreads from the place at which it first arose to distant locations in …