Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation

AE Morgan, KM Mooney, SJ Wilkinson, NA Pickles… - Ageing research …, 2016 - Elsevier
Cholesterol plays a vital role in the human body as a precursor of steroid hormones and bile
acids, in addition to providing structure to cell membranes. Whole body cholesterol …

Genetics, dyslipidemia, and cardiovascular disease: new insights

R Stein, F Ferrari, F Scolari - Current cardiology reports, 2019 - Springer
Abstract Purpose of Review The cardiovascular (CV) risk related to lipid disorders is well
established and is based on a robust body of evidence from well-designed randomized …

Lipoprotein lipase (LPL) polymorphism and the risk of coronary artery disease: a meta-analysis

L Xie, YM Li - International journal of environmental research and …, 2017 - mdpi.com
Background: In recent years, the lipoprotein lipase (LPL) polymorphism has been
extensively investigated as a potential risk factor for coronary artery disease (CAD) …

The association between FTO rs9939609 polymorphism and serum lipid profile in adult women

V Jalili, Z Mokhtari, S Rastgoo, A Hajipour… - Diabetology & Metabolic …, 2021 - Springer
Background FTO gene is considered to play an important role in many metabolic diseases.
Evidence from studies indicated the possible association between the FTO rs9939609 …

[PDF][PDF] Polymorphisms of lipid metabolism enzyme-coding genes in patients with diabetic dyslipidemia

AT Vardarlı, E Harman, VB Çetintaş… - … Anatolian Journal of …, 2017 - jag.journalagent.com
Objective: The polymorphisms/mutations of genes encoding proteins and enzymes involved
in lipoprotein metabolism play important roles in the development of diabetic dyslipidemia …

[HTML][HTML] The association of lipoprotein lipase genes, HindIII and S447X polymorphisms with coronary artery disease in Shiraz city

Z Ahmadi, S Senemar, S Toosi… - … of cardiovascular and …, 2015 - ncbi.nlm.nih.gov
Introduction: Several polymorphisms at the lipoprotein lipase (LPL) locus are associated
with variations in LPL activity serum lipid concentrations and the risk of coronary artery …

[HTML][HTML] Association between HindIII (rs320) variant in the lipoprotein lipase gene and the presence of coronary artery disease and stroke among the Saudi population

NM Bogari, A Aljohani, A Dannoun, O Elkhateeb… - Saudi Journal of …, 2020 - Elsevier
Lipoprotein Lipase (LPL) is known to be a key enzyme for lipid metabolism specifically in an
enzymatic glycoprotein which provide tissues without fatty-acids and eliminates triglycerides …

Dyslipidemia: Genetics, lipoprotein lipase and HindIII polymorphism

MP Rojas, C Prieto, V Bermúdez, C Garicano… - …, 2018 - pmc.ncbi.nlm.nih.gov
The direct link between lipid metabolism alterations and the increase of cardiovascular risk
are well documented. Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia …

Association of NFκβ, TNFα, IL-6, IL-1β, and LPL Polymorphisms with Type 2 Diabetes Mellitus and Biochemical Parameters in a Mexican Population

OC Martínez-Ramírez, DA Salazar-Piña… - Biochemical …, 2021 - Springer
Chronic low-grade inflammation is strongly related to the etiology of diabetes mellitus type 2
(T2DM), and the expression of inflammatory cytokines may be modulated by polymorphisms …

Associations between LPL gene polymorphisms and coronary artery disease: evidence based on an updated and cumulative meta-analysis

WQ Ma, Y Wang, XQ Han, Y Zhu, NF Liu - Bioscience reports, 2018 - portlandpress.com
Lipoprotein lipase (LPL) is widely linked to lipid and lipoprotein metabolism, but its effects on
coronary artery disease (CAD) are not clearly elucidated. The aim of the present study was …