Protein–protein interactions (PPIs) are essential in the regulation of biological functions and
cell events, therefore understanding PPIs have become a key issue to understanding the …

The gut microbiome is crucial for nutrient metabolism, immune regulation, and intestinal
homeostasis with changes in its composition linked to complex diseases like inflammatory …

Identification and analysis of host–pathogen interactions (HPI) is essential to study infectious
diseases. However, HPI data are sparse in existing molecular interaction databases …

While leading to millions of people's deaths every year the treatment of viral infectious
diseases remains a huge public health challenge. Therefore, an in-depth understanding of …

Motivation To complement experimental efforts, machine learning-based computational
methods are playing an increasingly important role to predict human–virus protein–protein …

Pathogens manipulate the cellular mechanisms of host organisms via pathogen–host
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …

Infectious diseases are still among the major and prevalent health problems, mostly
because of the drug resistance of novel variants of pathogens. Molecular interactions …

The diagnosis and treatment of bacterial infections in the medical and public health field in
the 21st century remain significantly challenging. Artificial Intelligence (AI) has emerged as a …

Abstract Analysis of degree centrality in conjunction with betweenness centrality of proteins
in a human protein-protein interaction network revealed three categories of centrally …

The mammalian immune system is a dynamic multiscale system composed of a
hierarchically organized set of molecular, cellular, and organismal networks that act in …