Pan-and isoform-specific inhibition of Hsp90: Design strategy and recent advances
J Yu, C Zhang, C Song - European Journal of Medicinal Chemistry, 2022 - Elsevier
In the past few decades, the development of heat shock protein 90 (Hsp90) inhibitors for
cancer treatment has not stopped. About twenty compounds have been evaluated in the …
cancer treatment has not stopped. About twenty compounds have been evaluated in the …
Heat shock proteins and cancer: How can nanomedicine be harnessed?
F Sauvage, S Messaoudi, E Fattal, G Barratt… - Journal of Controlled …, 2017 - Elsevier
Heat shock protein (hsp90) is an interesting target for cancer therapy because it is involved
in the folding and stabilization of numerous proteins, including many that contribute to the …
in the folding and stabilization of numerous proteins, including many that contribute to the …
Mitochondria-mediated HSP inhibition strategy for enhanced low-temperature photothermal therapy
W Liu, J Di, Y Ma, S Wang, M Meng, Y Yin… - … Applied Materials & …, 2023 - ACS Publications
Low-temperature photothermal therapy (PTT) has the advantage of causing less damage to
normal tissues and has attracted great attention in recent years. However, the efficacy of low …
normal tissues and has attracted great attention in recent years. However, the efficacy of low …
Artesunate, as a HSP70 ATPase activity inhibitor, induces apoptosis in breast cancer cells
The present study aims to evaluate the inhibitory effects of artesunate (a semi-synthetic
derivative of artemisinin) on HSP70 and Bcl-2 expression in two breast cancer cell lines, 4T1 …
derivative of artemisinin) on HSP70 and Bcl-2 expression in two breast cancer cell lines, 4T1 …
[HTML][HTML] 热休克蛋白的功能及其在畜牧业中的应用
唐姝， 徐蛟， 狄良娇， 殷斌， 孙家瑞， 鲍恩东 - 南京农业大学学报, 2018 - html.rhhz.net
作为分子伴侣, 热休克蛋白(HSP) 可以参与到各种生命活动中. 其最主要的功能是帮助错误折叠
蛋白回到原来的状态, 维持细胞的稳态. 很多研究都表明HSP 可以参与免疫, 抗氧化 …
蛋白回到原来的状态, 维持细胞的稳态. 很多研究都表明HSP 可以参与免疫, 抗氧化 …