The mechanisms of arsenic-induced ovotoxicity, ultrastructural alterations, and autophagic related paths: An enduring developmental study in folliculogenesis of mice

MM Ommati, X Shi, H Li, MJ Zamiri, O Farshad… - Ecotoxicology and …, 2020 - Elsevier
Arsenic (As) exerts a wide range of adverse effects on biological systems, including the
reproductive organs in males and females. However, the mechanisms of As-induced …

Glycine protects the male reproductive system against lead toxicity via alleviating oxidative stress, preventing sperm mitochondrial impairment, improving kinematics of …

MM Ommati, HN Ahmadi, S Sabouri… - Environmental …, 2022 - Wiley Online Library
Lead (Pb) is a highly toxic heavy metal widely dispersed in the environment because of
human industrial activities. Many studies revealed that Pb could adversely affect several …

The activation of nuclear factor-E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling blunts cholestasis-induced liver and kidney injury

K Mousavi, H Niknahad, H Li, Z Jia… - Toxicology …, 2021 - academic.oup.com
Cholestasis is a severe clinical complication that severely damages the liver. Kidneys are
also the most affected extrahepatic organs in cholestasis. The pivotal role of oxidative stress …

Fluoride exposure induces mitochondrial damage and mitophagy via activation of the IL-17A pathway in hepatocytes

Y Zhao, J Wang, J Zhang, Z Sun, R Niu… - Science of the Total …, 2022 - Elsevier
As an environmental toxicant, the damage of fluoride to the body has attracted global
attention. Because liver is an essential organ for fluoride accumulation and damage. Our …

The crucial role of oxidative stress in non-alcoholic fatty liver disease-induced male reproductive toxicity: the ameliorative effects of Iranian indigenous probiotics

MM Ommati, H Li, A Jamshidzadeh… - Naunyn-Schmiedeberg's …, 2022 - Springer
Several studies have focused on the high potential effects of probiotics on the reproductive
system. However, there is a paucity of information regarding the ameliorative intracellular …

[HTML][HTML] Molecular insights into experimental models and therapeutics for cholestasis

W Zhang, H Wu, S Luo, X Lu, X Tan, L Wen… - Biomedicine & …, 2024 - Elsevier
Cholestatic liver disease (CLD) is a range of conditions caused by the accumulation of bile
acids (BAs) or disruptions in bile flow, which can harm the liver and bile ducts. To investigate …

Taurine and isolated mitochondria: A concentration-response study

H Mohammadi, MM Ommati, O Farshad… - Trends in …, 2019 - tips.sums.ac.ir
Taurine (TAU) is the most abundant free amino acid in the human body. High concentrations
of this amino acid are found in tissues such as the skeletal muscle, brain, and kidney …

Profile of bile acid metabolomics in the follicular fluid of PCOS patients

X Yang, R Wu, D Qi, L Fu, T Song, Y Wang, Y Bian… - Metabolites, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex heterogeneous endocrine disease affected
by genetic and environmental factors. In this manuscript, we aimed to describe the …

The role of mitochondrial impairment and oxidative stress in the pathogenesis of lithium-induced reproductive toxicity in male mice

MM Ommati, MR Arabnezhad, O Farshad… - Frontiers in Veterinary …, 2021 - frontiersin.org
Lithium (Li+) is prescribed against a wide range of neurological disorders. Besides its
excellent therapeutic properties, there are several adverse effects associated with Li+. The …

Cholestasis-associated pulmonary inflammation, oxidative stress, and tissue fibrosis: The protective role of the biogenic amine agmatine

MM Ommati, H Niknahad, A Najibi, A Arjmand… - Pharmacology, 2023 - karger.com
Introduction: Cholestasis is the stoppage of bile flow, leading to the accumulation of
potentially cytotoxic bile components in the liver. These cytotoxic molecules affect many …