Established human cancer cell lines are routinely used as experimental models for human
cancers. Their validity for such use is analyzed and discussed, with particular focus on …

Human thyroid cancer cell lines are the most used models for thyroid cancer studies. They
must be used with detailed knowledge of their characteristics. These in vitro cell lines …

Context: Cell lines derived from human cancers provide critical tools to study disease
mechanisms and develop novel therapies. Recent reports indicate that up to 36% of cell …

Oncocytic cell tumors are characterized by the accumulation of morphologically abnormal
mitochondria in their cells, suggesting a role for abnormal mitochondrial biogenesis in …

Although tyrosine-phosphorylated or activated STAT3 (pY-STAT3) is a well-described
mediator of tumorigenesis, its role in thyroid cancer has not been investigated. We observed …

Thyroid cancer is the most common endocrine cancer, with differentiated thyroid cancers
(DTCs) accounting for 95% of diagnoses. While most DTC patients are diagnosed and …

Background Chimeric antigen receptor T cells (CAR-Ts) have demonstrated remarkable
efficacy in hematological cancers but have not yet translated in treating solid tumors. The …

Recent advances in the arena of theranostics have necessitated a re-examining of
previously established fields. The existing paradigm of therapeutic thyroid-stimulating …

Abstract Purpose. B‐RafV600E may play a role in the progression from papillary thyroid
cancer to anaplastic thyroid cancer (ATC). We tested the effects of a highly selective B …

TAGLN2, an actin-binding protein, functions as a binding protein to actin to facilitate the
formation of intracellular cytoskeleton structures. TAGLN2 overexpression in papillary …