Roles of glutamate receptors in Parkinson's disease

Z Zhang, S Zhang, P Fu, Z Zhang, K Lin… - International journal of …, 2019 - mdpi.com
Parkinson's disease is a progressive neurodegenerative disorder resulting from the
degeneration of pigmented dopaminergic neurons in the substantia nigra pars compacta. It …

The promise of the zebrafish model for Parkinson's disease: Today's science and tomorrow's treatment

K Razali, N Othman, MH Mohd Nasir… - Frontiers in …, 2021 - frontiersin.org
The second most prevalent neurodegenerative disorder in the elderly is Parkinson's disease
(PD). Its etiology is unclear and there are no available disease-modifying medicines …

Molecular mechanism of cognitive impairment associated with Parkinson's disease: A stroke perspective

S Gupta, J Khan, S Ghosh - Life Sciences, 2024 - Elsevier
Parkinson's disease (PD) is a common neurological illness that causes several motor and
non-motor symptoms, most characteristically limb tremors and bradykinesia. PD is a slowly …

Glutamate Receptor Dysregulation and Platelet Glutamate Dynamics in Alzheimer's and Parkinson's Diseases: Insights into Current Medications

D Gautam, UP Naik, MU Naik, SK Yadav… - Biomolecules, 2023 - mdpi.com
Two of the most prevalent neurodegenerative disorders (NDDs), Alzheimer's disease (AD)
and Parkinson's disease (PD), present significant challenges to healthcare systems …

Prelimbic cortical projections to rostromedial tegmental nucleus play a suppressive role in cue-induced reinstatement of cocaine seeking

AM Cruz, HF Spencer, TH Kim, TC Jhou… - …, 2021 - nature.com
The prelimbic (PL) region of prefrontal cortex has been implicated in both driving and
suppressing cocaine seeking in animal models of addiction. We hypothesized that these …

Exogenous adenosine antagonizes excitatory amino acid toxicity in primary astrocytes

Y Liu, S Chu, Y Hu, S Yang, X Li, Q Zheng, Q Ai… - Cellular and Molecular …, 2021 - Springer
Excitatory toxicity is still a hot topic in the study of ischemic stroke, and related research has
focused mainly on neurons. Adenosine is an important neuromodulator that is known as a …

谷氨酸受体在帕金森病中的作用及其介导的帕金森病运动防治研究进展

陈平, 李刚强, 周文辉 - 体育科学, 2022 - tykx.xml-journal.net
帕金森病(Parkinson's disease, PD) 是一种复杂的神经退行性疾病, 严重影响中老年人的健康及
生活质量. 中脑黑质致密部多巴胺(dopamine, DA) 能神经元变性丢失导致基底神经节(basal …

Parkinson's Disease: An Overview and Role of Glutamate and its Receptors: Glutamate receptor based therapy as an alternate way to treat Parkinson's

D Yadav, P Kumar - 2021 5th International Conference on …, 2021 - ieeexplore.ieee.org
Among several neurodegenerative disorders, Parkinson's is one of the utmost widespread
diseases, occur due to the degeneration of the dopaminergic neurons in the region of …

[HTML][HTML] Human iPSC genetically encoded fluorescent biosensor models for toxicity imaging

D Stellon - 2024 - figshare.utas.edu.au
The brain is the most complex organ in the human body, consisting primarily of various types
of neurons and non-neuronal cells, known as neuroglia. In disease, these distinct cell …

Differential susceptibility to reduced dopamine in SNc versus VTA in a mouse Tyrosine hydroxylase KO model of Parkinson's Disease

M Koltun, K Cichewicz, JT Gibbs, M Darvas, J Hirsh - bioRxiv, 2018 - biorxiv.org
Abstract Parkinson's Disease (PD), is a neurodegenerative disorder affecting both cognitive
and motor functions. It is characterized by decreased brain dopamine (DA) and a selective …