Advanced nitric oxide generating nanomedicine for therapeutic applications

Z Wang, A Jin, Z Yang, W Huang - ACS nano, 2023 - ACS Publications
Nitric oxide (NO), a gaseous transmitter extensively present in the human body, regulates
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …

Current status and prospects of metal–organic frameworks for bone therapy and bone repair

M Li, S Yin, M Lin, X Chen, Y Pan, Y Peng… - Journal of Materials …, 2022 - pubs.rsc.org
With the development of society, traumatic bone defects caused by accidents, diseases and
surgeries have become common, eventually resulting in an increase in bone defects. The …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Nanocatalyst‐mediated chemodynamic tumor therapy

L Zhang, CX Li, SS Wan… - Advanced healthcare …, 2022 - Wiley Online Library
Traditional tumor treatments, including chemotherapy, radiotherapy, photodynamic therapy,
and photothermal therapy, are developed and used to treat different types of cancer …

Sustained release of nitric oxide and cascade generation of reactive nitrogen/oxygen species via an injectable hydrogel for tumor synergistic therapy

Y Wang, X Yang, X Chen, X Wang… - Advanced Functional …, 2022 - Wiley Online Library
Reactive nitrogen species (RNS) generated via the reaction of nitric oxide (NO) with reactive
oxygen species (ROS) are more lethal than ROS, and thus RNS‐mediated therapy has great …

Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Recent progress of metal‐based nanomaterials with anti‐tumor biological effects for enhanced cancer therapy

H Lei, Z Pei, C Jiang, L Cheng - Exploration, 2023 - Wiley Online Library
Metal‐based nanomaterials have attracted broad attention recently due to their unique
biological physical and chemical properties after entering tumor cells, namely biological …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy

M Shi, J Zhang, Y Wang, C Peng, H Hu, M Qiao… - Biomaterials, 2022 - Elsevier
Multiple biological barriers and tumor metastasis severely impede the tumor therapy. To
address these adversities, an acid-activated poly (ethylene glycol)-poly-l-lysine-2, 3 …

Metal–organic frameworks (MOFs) for cancer therapy

MR Saeb, N Rabiee, M Mozafari, F Verpoort… - Materials, 2021 - mdpi.com
MOFs exhibit inherent extraordinary features for diverse applications ranging from catalysis,
storage, and optics to chemosensory and biomedical science and technology. Several …