Cellular mechanisms of liver regeneration and cell‐based therapies of liver diseases

IV Kholodenko, KN Yarygin - BioMed research international, 2017 - Wiley Online Library
The emerging field of regenerative medicine offers innovative methods of cell therapy and
tissue/organ engineering as a novel approach to liver disease treatment. The ultimate …

Liver-resident NK cells suppress autoimmune cholangitis and limit the proliferation of CD4+ T cells

ZB Zhao, FT Lu, HD Ma, YH Wang, W Yang… - Cellular & Molecular …, 2020 - nature.com
Liver-resident NK cells are distinct from conventional NK cells and play an important role in
the maintenance of liver homeostasis. How liver-resident NK cells participate in autoimmune …

[HTML][HTML] Liver regeneration in chronic liver injuries: Basic and clinical applications focusing on macrophages and natural killer cells

Y Qian, Z Shang, Y Gao, H Wu, X Kong - Cellular and Molecular …, 2022 - Elsevier
Background & Aims Liver regeneration is a necessary but complex process involving
multiple cell types besides hepatocytes. Mechanisms underlying liver regeneration after …

[HTML][HTML] Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicity

L Yu, J Yan, Y Zhan, A Li, L Zhu, J Qian, F Zhou… - Journal of …, 2023 - Elsevier
Gaining a better understanding of autoprotection against drug-induced liver injury (DILI) may
provide new strategies for its prevention and therapy. However, little is known about the …

Liver regeneration supported by muse cells

SS Nishizuka, Y Suzuki, H Katagiri… - Muse Cells: Endogenous …, 2018 - Springer
Cellular compensation from extrahepatic resources is expected to improve the prognosis of
liver diseases. Currently, liver dysfunction is treated by a variety of modalities including …

[HTML][HTML] Hedgehog signaling pathway regulates liver regeneration in the Fah-/-knockout mice model xenografted by human hepatocytes

X Xu, X Jiao, Y Jiao, M Wang, C Jiao - International journal of …, 2017 - ncbi.nlm.nih.gov
Background: The aim of this study is to evaluates the hypothesis that Hh pathway activation
occurs in the Fah-/-Nod/Scid mice model and plays a role in regulating liver regeneration …

[PDF][PDF] Stem Cell Therapeutics of Acute Liver Diseases, Transplantation, and Regeneration

RK Upadhyay - J Cell Sci Ther, 2017 - researchgate.net
Present review article explains various causes of acute liver diseases and their therapeutics.
This article describes major reasons of hepatic pathophysiological conditions and diseases …

Rôle de la Reptine in vivo dans la physiopathologie hépatique

J Javary - 2017 - theses.hal.science
Les travaux antérieurs du laboratoire ont montré que la Reptine, une AAA+ ATPase, est
surexprimée dans le carcinome hépatocellulaire où elle est nécessaire à la prolifération et …