The field of chronic lymphocytic leukemia (CLL) has witnessed considerable change since
the time clinical staging was introduced in clinical practice in 1975. Over the years, the …

Over the past three decades, considerable efforts have been expended on understanding
the Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling …

Background The management of patients with chronic lymphocytic leukaemia is currently
undergoing improvements due to novel therapies and a plethora of biological and genetic …

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world
with an incidence of 4.2/100 000/year. The incidence increases to more than 30/100 …

Importance The most common leukemia is chronic lymphocytic leukemia (CLL). Every year,
there are 15 000 new diagnoses and 5000 CLL deaths in the United States. Although …

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world with
an incidence of 4.2/100 000/year [1]. The incidence increases to> 30/100 000/year at an age …

The article provides information on diagnosis and management of chronic lymphocytic
leukemia (CLL). It informs about diagnosis of the CLL which includes lymphocyte …

The long-established notion that apoptosis would be immunologically silent, and hence it
would go unnoticed by the immune system, if not tolerogenic, and hence it would actively …

The present review deals with current advances in the chemoenzymatic synthesis of
biologically important nucleoside analogues (NA), either by the use of microorganisms or …

Purine nucleoside analogs (PNAs) compose a class of cytotoxic drugs that have played an
important role in the treatment of hematological neoplasms, especially lymphoid and …