Diffusion-weighted and Perfusion MR Imaging for Brain Tumor Characterization and Assessment of Treatment Response1

JM Provenzale, S Mukundan, DP Barboriak - Radiology, 2006 - pubs.rsna.org
Diffusion-weighted magnetic resonance (MR) imaging and perfusion MR imaging are
advanced techniques that provide information not available from conventional MR imaging …

Imaging tumor vascular heterogeneity and angiogenesis using dynamic contrast-enhanced magnetic resonance imaging

A Jackson, JPB O'Connor, GJM Parker… - Clinical Cancer Research, 2007 - AACR
This article reviews the application of dynamic contrast-enhanced magnetic resonance
imaging in both clinical studies and early-phase trials of angiogenesis inhibitors. Emphasis …

Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to …

LS Hu, JM Eschbacher, JE Heiserman… - Neuro …, 2012 - academic.oup.com
Abstract INTRODUCTION: Contrast-enhanced MRI (CE-MRI) represents the current
mainstay for monitoring treatment response in glioblastoma multiforme (GBM), based on the …

Pitfalls in the neuroimaging of glioblastoma in the era of antiangiogenic and immuno/targeted therapy–detecting illusive disease, defining response

RY Huang, MR Neagu, DA Reardon, PY Wen - Frontiers in neurology, 2015 - frontiersin.org
Glioblastoma, the most common malignant primary brain tumor in adults is a devastating
diagnosis with an average survival of 14–16 months using the current standard of care …

Principles of T2*‐weighted dynamic susceptibility contrast MRI technique in brain tumor imaging

MS Shiroishi, G Castellazzi… - Journal of magnetic …, 2015 - Wiley Online Library
Dynamic susceptibility contrast magnetic resonance imaging (DSC‐MRI) is used to track the
first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue …

Improved 3D quantitative mapping of blood volume and endothelial permeability in brain tumors

KL Li, XP Zhu, J Waterton… - Journal of Magnetic …, 2000 - Wiley Online Library
We describe a new method to allow simultaneous mapping of endothelial permeability and
blood volume in intracranial lesions. The technique is based on a tumor leakage profile …

Optimized preload leakage-correction methods to improve the diagnostic accuracy of dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in …

LS Hu, LC Baxter, DS Pinnaduwage… - American Journal …, 2010 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) accuracy can vary
substantially depending on the dynamic susceptibility-weighted contrast-enhanced (DSC) …

Dynamic susceptibility-weighted perfusion imaging of high-grade gliomas: characterization of spatial heterogeneity

JM Lupo, S Cha, SM Chang… - American Journal of …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The advent of new anti-angiogenic therapies has created
the need for better defining regions of abnormal vascularity in order to add specificity to the …

Distinguishing recurrent high-grade gliomas from radiation injury: a pilot study using dynamic contrast-enhanced MR imaging

S Bisdas, T Naegele, R Ritz, A Dimostheni… - Academic radiology, 2011 - Elsevier
RATIONALE AND OBJECTIVES: The accurate delineation of tumor recurrence and its
differentiation from radiation injury in the follow-up of adjuvantly treated high-grade gliomas …

Correlations between perfusion MR imaging cerebral blood volume, microvessel quantification, and clinical outcome using stereotactic analysis in recurrent high …

LS Hu, JM Eschbacher, AC Dueck… - American Journal …, 2012 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Quantifying MVA rather than MVD provides better
correlation with survival in HGG. This is attributed to a specific “glomeruloid” vascular …