Emergence of the fungal immune system

A Daskalov - Iscience, 2023 - cell.com
Investigation of fungal biology has been frequently motivated by the fact that many fungal
species are important plant and animal pathogens. Such efforts have contributed …

Longevity of Fungal Mycelia and Nuclear Quality Checks: a New Hypothesis for the Role of Clamp Connections in Dikaryons

DK Aanen, A van't Padje, B Auxier - Microbiology and Molecular …, 2023 - Am Soc Microbiol
This paper addresses the stability of mycelial growth in fungi and differences between
ascomycetes and basidiomycetes. Starting with general evolutionary theories of …

A moonlighting function of a chitin polysaccharide monooxygenase, CWR-1, in Neurospora crassa allorecognition

TC Detomasi, AM Rico-Ramírez, RI Sayler… - elife, 2022 - elifesciences.org
Organisms require the ability to differentiate themselves from organisms of different or even
the same species. Allorecognition processes in filamentous fungi are essential to ensure …

Gasdermin and gasdermin-like pore-forming proteins in invertebrates, fungi and bacteria

A Daskalov, NL Glass - Journal of molecular biology, 2022 - Elsevier
The gasdermin family of pore-forming proteins (PFPs) has recently emerged as key
molecular players controlling immune-related cell death in mammals. Characterized …

Microbial gasdermins: More than a billion years of pyroptotic-like cell death

Q Zheng, A Daskalov - Seminars in immunology, 2023 - Elsevier
In the recent past, the concept of immunity has been extended to eukaryotic and prokaryotic
microorganisms, like fungi and bacteria. The latest findings have drawn remarkable …

Targeted hypermutation of putative antigen sensors in multicellular bacteria

H Doré, AR Eisenberg, EN Junkins… - Proceedings of the …, 2024 - National Acad Sciences
Diversity-generating retroelements (DGRs) are used by bacteria, archaea, and viruses as a
targeted mutagenesis tool. Through error-prone reverse transcription, DGRs introduce …

An apoptosis-inducing factor controls programmed cell death and laccase expression during fungal interactions

J Fang, G Zhou, H Zhao, D Xie, J Zhang, U Kües… - Applied Microbiology …, 2024 - Springer
Apoptotic-like programmed cell death (PCD) is one of the main strategies for fungi to resist
environmental stresses and maintain homeostasis. The apoptosis-inducing factor (AIF) has …

Fungal cell death: the beginning of the end

AM Rico-Ramírez, AP Gonçalves, NL Glass - Fungal Genetics and Biology, 2022 - Elsevier
Death is an important part of an organism's existence and also marks the end of life. On a
cellular level, death involves the execution of complex processes, which can be classified …

Amyloid signaling in filamentous fungi and bacteria

SJ Saupe - Annual review of microbiology, 2020 - annualreviews.org
Amyloids are implicated in many protein misfolding diseases. Amyloid folds, however, also
display a range of functional roles particularly in the microbial world. The templating ability of …

Highly conserved, but highly specific: somatic cell–cell fusion in filamentous fungi

A Fleißner, AG Oostlander, L Well - Current Opinion in Cell Biology, 2022 - Elsevier
The development of ascomycete fungal colonies involves cell–cell fusion at different growth
stages. In the model fungus Neurospora crassa, communication of two fusing cells is …