Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies

E Derisoud, H Jiang, A Zhao… - Human …, 2024 - academic.oup.com
BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …

Single-cell immunobiology of the maternal–fetal interface

D Miller, V Garcia-Flores, R Romero… - The Journal of …, 2022 - journals.aai.org
Pregnancy success requires constant dialogue between the mother and developing
conceptus. Such crosstalk is facilitated through complex interactions between maternal and …

The COVID-19 pandemic and pregnancy: Impact on mothers and newborns

JDE Twanow, C McCabe, MA Ream - Seminars in Pediatric Neurology, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus 2 pandemic has markedly, and likely
permanently, changed health care. This includes changing the obstetric and perinatal care …

SARS-CoV-2 niches in human placenta revealed by spatial transcriptomics

ER Barrozo, MD Seferovic, ECC Castro, AM Major… - Med, 2023 - cell.com
Background Functional placental niches are presumed to spatially separate maternal-fetal
antigens and restrict the vertical transmission of pathogens. We hypothesized a high …

Placental single cell transcriptomics: Opportunities for endocrine disrupting chemical toxicology

ER Elkin, KA Campbell, S Lapehn, SM Harris… - Molecular and Cellular …, 2023 - Elsevier
The placenta performs essential biologic functions for fetal development throughout
pregnancy. Placental dysfunction is at the root of multiple adverse birth outcomes such as …

Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy

C Xi, Z Yan, D Bai, Y Zhang, B Wang, X Han… - Protein & …, 2024 - academic.oup.com
The current coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus (SARS-CoV-2) remains a threat to pregnant women …

Immune repertoire analysis of normal Chinese donors at different ages

C Song, W Pan, B Brown, C Tang, Y Huang… - Cell …, 2022 - Wiley Online Library
Objectives This study investigated the characteristics of the immune repertoire in normal
Chinese individuals of different ages. Materials and Methods In this study, all seven receptor …

Do chemokine/chemokine receptor axes play paramount parts in trafficking and oriented locomotion of monocytes/macrophages toward the lungs of COVID-19 …

M Mahmoodi, FM Henjeroei, G Hassanshahi… - Cytokine, 2024 - Elsevier
Abstract The COVID-19 (coronavirus disease 2019) is a well-defined viral infection, resulting
from SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2). The innate immune …

Possibility of intrauterine transmission from mother to fetus/newborn: systematic review and meta-analysis of diagnostic methods to detect SARS-CoV-2 infection

P Khodavandi, A Khodavandi, F Alizadeh… - European Journal of …, 2024 - Elsevier
Several studies have reported vertical transmission of SARS-CoV-2; however, information
regarding intrauterine transmission based on diagnostic methods to detect SARS-CoV-2 …

Endocytosis at the maternal-fetal interface: balancing nutrient transport and pathogen defense

M Fan, H Wu, AN Sferruzzi-Perri, YL Wang… - Frontiers in …, 2024 - frontiersin.org
Endocytosis represents a category of regulated active transport mechanisms. These
encompass clathrin-dependent and-independent mechanisms, as well as fluid phase …