Organotropism has been known since 1889, yet this vital component of metastasis has
predominantly stayed elusive. This mini-review gives an overview of the current …

The origin of metastases is a topic that has sparked controversy. Despite recent
advancements, metastatic disease continues to pose challenges. The first admitted model of …

Metastases from primary prostate cancers to rare locations, such as the brain, are becoming
more common due to longer life expectancy resulting from improved treatments. Epigenetic …

Previous studies from our lab demonstrated that the crosstalk between brain-metastasizing
melanoma cells and microglia, the macrophage-like cells of the central nervous system …

MCF7 is a commonly used luminal type A non-invasive/poor-invasive human breast cancer
cell line that does not usually migrate or invade compared with MDA-MB-231 highly …

Background and aims The actual classification of breast tumors in subtypes represents an
attempt to stratify patients into clinically cohesive groups, nevertheless, clinicians still lack …

Human jumping translocation breakpoint (hJTB) gene is located on chromosome 1q21 and
is involved in unbalanced translocation in many types of cancer. JTB protein is ubiquitously …

Introduction Regarding whether brain magnetic resonance imaging (MRI) should be routine
in patients with suspected early-stage lung cancer, guideline recommendations are …

Aim: To delineate the transcriptomic landscape and potential molecular mechanisms of
breast cancer brain metastasis (BCBM). Materials&methods: Whole-transcriptome …

The disordered growth, invasion and metastasis of cancer are mainly attributed to
bidirectional cell-cell interactions. Extracellular vesicles (EVs) secreted by cancer cells are …