Metabolites are intermediate products of cellular metabolism catalysed by various enzymes.
Metabolic remodelling, as a biochemical fingerprint of cancer cells, causes abnormal …

Human hepatitis B virus (HBV) is a small enveloped DNA virus with a complex life cycle. It is
the causative agent of acute and chronic hepatitis. HBV can resist immune system …

Chronic hepatitis B virus (HBV) infection remains a major health burden worldwide for which
there is still no effective curative treatment. Interferon (IFN) consists of a group of cytokines …

Hepatitis B virus infection affects over 250 million chronic carriers, causing more than
800,000 deaths annually, although a safe and effective vaccine is available. Currently used …

Protein post‐translational modifications (PTMs) of histones are ubiquitous regulatory
mechanisms involved in many biological processes, including replication, transcription, DNA …

Succinylation is a post-translational modification (PTM) event that associates metabolic
reprogramming with various pathological disorders including cancers via transferring a …

Metabolic reprogramming is a common hallmark of cancers and involves alterations in many
metabolic pathways during tumor initiation and progression. However, the cancer-specific …

Chronic hepatitis B virus (HBV) infection is an international health problem with extremely
high mortality and morbidity rates. Although current clinical chronic hepatitis B (CHB) …

Hepatitis B virus (HBV) infection remains a major health problem worldwide. Sufficient
maintenance of the HBV covalently closed circular DNA (cccDNA), which serves as a …

Occult hepatitis B virus (HBV) infection (OBI) refers to the presence of replication-competent
HBV DNA in the liver, with or without HBV DNA in the blood, in individuals who tested …