Conspectus To improve the efficacy of molecular syntheses, researchers wish to capitalize
upon the selective modification of otherwise inert C–H bonds. The past two decades have …

As a rapidly growing field across all areas of chemistry, CH activation/functionalisation is
being used to access a wide range of important molecular targets. Of particular interest is the …

Conspectus Aromatic structures are widespread motifs throughout organic chemistry, and C–
H activation has been recognized as a major tool for enabling their sustainable and efficient …

Enantioselective C–H functionalization is a powerful tool for synthesizing chiral molecules.
In the past few years, the combination of high-valent group 9 metals with achiral Cpx ligands …

Satoh–Miura reaction is an important method for extending π‐systems by forging multi‐
substituted benzene rings via double aryl C− H activation and annulation with alkynes …

The mechanochemical, solvent‐free, highly regioselective, rhodium‐catalyzed C− H
methylation of (hetero) arenes is reported. The reaction shows excellent functional‐group …

The electrochemical transition metal-catalyzed cross-dehydrogenative reaction has
emerged as a promising platform to achieve a sustainable and atom-economic organic …

Detailed density functional theory calculations provide valuable insight into reactivity-
controlling factors in transition metal-catalyzed C–H activation by carboxylate assistance …

Protonation of C–M bonds and its microscopic reverse, metalation of C–H bonds, are
fundamental steps in a variety of metal-catalyzed processes. As such, studies on protonation …

Rhodium (III) catalysis has set the stage for a plethora of oxidative C–H functionalizations
over the last decade, which have predominantly employed stoichiometric amounts of toxic …