Transcriptional state dynamics lead to heterogeneity and adaptive tumor evolution in urothelial bladder carcinoma

A Biswas, S Sahoo, GM Riedlinger… - Communications …, 2023 - nature.com
Intra-tumor heterogeneity contributes to treatment failure and poor survival in urothelial
bladder carcinoma (UBC). Analyzing transcriptome from a UBC cohort, we report that intra …

Epithelial to Mesenchymal Transition: A Challenging Playground for Translational Research. Current Models and Focus on TWIST1 Relevance and Gastrointestinal …

L Greco, F Rubbino, A Morelli, F Gaiani… - International Journal of …, 2021 - mdpi.com
Resembling the development of cancer by multistep carcinogenesis, the evolution towards
metastasis involves several passages, from local invasion and intravasation, encompassing …

GIMAP7 as a potential predictive marker for pan-cancer prognosis and immunotherapy efficacy

Y Qin, H Liu, X Huang, L Huang, L Liao… - Journal of …, 2022 - Taylor & Francis
Background GIMAP, a GTP enzyme of immune-related proteins, plays a crucial role in
immune mechanisms. Investigating GIMAP7 expression in pan-cancer can provide efficient …

The combined tumour-based Fascin/Snail and stromal periostin reveals the effective prognosis prediction in colorectal cancer patients

N Jirapongwattana, S Thongchot, A Pongpaibul… - Plos one, 2024 - journals.plos.org
Colorectal cancer (CRC) is the third most common malignancy cause of cancer-related
mortality worldwide. Epithelial-mesenchymal transition (EMT) promotes cancer metastasis …

Prognostic Signature in Osteosarcoma Based on Amino Acid Metabolism-Associated Genes

L Feng, Y Chen, X Mei, L Wang, W Zhao… - Cancer Biotherapy & …, 2024 - liebertpub.com
Background: Osteosarcoma (OS) is undeniably a formidable bone malignancy characterized
by a scarcity of effective treatment options. Reprogramming of amino acid (AA) metabolism …

Constructing a personalized prognostic risk model for colorectal cancer using machine learning and multi‐omics approach based on epithelial–mesenchymal …

S Zhang, W Fan, D He - The Journal of Gene Medicine, 2024 - Wiley Online Library
The progression and the metastatic potential of colorectal cancer (CRC) are intricately linked
to the epithelial–mesenchymal transition (EMT) process. The present study harnesses the …