Therapeutic advances of targeting receptor tyrosine kinases in cancer

C Tomuleasa, AB Tigu, R Munteanu… - … and Targeted Therapy, 2024 - nature.com
Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained
significant clinical attention in oncology due to their central role in cancer pathogenesis …

Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche

Y Henlon, K Panir, I McIntyre, C Hogg, P Dhami… - Proceedings of the …, 2024 - pnas.org
Endometriosis negatively impacts the health-related quality of life of 190 million women
worldwide. Novel advances in nonhormonal treatments for this debilitating condition are …

Recent discovery and development of AXL inhibitors as antitumor agents

Z Liu, L Chen, J Zhang, J Yang, X Xiao, L Shan… - European Journal of …, 2024 - Elsevier
ABSTRACT AXL, a receptor tyrosine kinase (RTK), plays a pivotal role in various cellular
functions. It is primarily involved in processes such as epithelial-mesenchymal transition …

[HTML][HTML] Functions of TAM Receptors and Ligands Protein S and Gas6 in Atherosclerosis and Cardiovascular Disease

T Prouse, S Majumder, R Majumder - International Journal of Molecular …, 2024 - mdpi.com
Atherosclerosis and cardiovascular disease are associated with high morbidity and mortality
in industrialized nations. The Tyro3, Axl, and Mer (TAM) family of receptor tyrosine kinases is …

AXL receptor tyrosine kinase modulates gonadotropin-releasing hormone receptor signaling

P Mohammadzadeh, M Roueinfar… - Cell Communication and …, 2023 - Springer
Abstract Background Gonadotropin-releasing hormone (GnRH) receptors are essential for
reproduction and are expressed in numerous urogenital, reproductive, and non-reproductive …

Defective macrophage efferocytosis in advanced atherosclerotic plaque and mitochondrial therapy

W Li, Y Huang, J Liu, Y Zhou, H Sun, Y Fan, F Liu - Life Sciences, 2024 - Elsevier
Atherosclerosis (AS) is a chronic inflammatory disease primarily affecting large and medium-
sized arterial vessels, characterized by lipoprotein disorders, intimal thickening, smooth …

AXL/GAS6 signaling governs differentiation of tumor-associated macrophages in breast cancer

S Purohit, G Mandal, S Biswas, S Dalui, A Gupta… - Experimental Cell …, 2025 - Elsevier
Most epithelial cancers are infiltrated by prognostically relevant myelomonocytic cells.
Immunosuppressive tumor associated macrophages (TAMs) and their precursor monocytic …

维生素K2 在化妆品中的应用研究进展.

徐春潇, 柳晨 - Detergent & Cosmetics, 2024 - search.ebscohost.com
维生素K2在化妆品中的应用研究进展 Page 1 Technique express 科技广场 54 Vol.47 No.6 Jun.
2024 维生素K2是维生素K家族中的一种脂溶性维生素. 维生素K,尤其是维生素K2,是一个重要的 …

[PDF][PDF] Functions of TAM Receptors and Their Ligands Protein S and Gas6 in Atherosclerosis and Cardiovascular

T Prouse, S Majumder, R Majumder - 2024 - preprints.org
Atherosclerosis and cardiovascular disease are associated with high morbidity and mortality
in industrialized nations. The Tyro3, Axl, and Mer (TAM) family of receptor tyrosine kinases is …

Targeted therapies for Malignant Mesothelioma

V Angiolini - 2025 - tesidottorato.depositolegale.it
Malignant mesothelioma (MM) is an aggressive neoplasia arising from mesothelial cells that
line serous cavities, such as pleura, peritoneum, pericardium, and vaginal tunic. It is defined …