Mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment

VJ Clemente-Suárez, A Martín-Rodríguez… - International Journal of …, 2023 - mdpi.com
Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …

Challenges in promoting mitochondrial transplantation therapy

Y Yamada, M Ito, M Arai, M Hibino, T Tsujioka… - International Journal of …, 2020 - mdpi.com
Mitochondrial transplantation therapy is an innovative strategy for the treatment of
mitochondrial dysfunction. The approach has been reported to be useful in the treatment of …

Effects of mitochondrial transplantation on bioenergetics, cellular incorporation, and functional recovery after spinal cord injury

JL Gollihue, SP Patel, KC Eldahan, DH Cox… - Journal of …, 2018 - liebertpub.com
Our previous studies reported that pharmacological maintenance of mitochondrial
bioenergetics after experimental spinal cord injury (SCI) provided functional …

Therapeutic applications of mitochondrial transplantation

O Ulger, GB Kubat - Biochimie, 2022 - Elsevier
This review aims to make a framework of exogenous healthy mitochondrial transplantation
and to assemble present information for improving new therapeutic applications in a variety …

Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria

G Ramirez-Barbieri, K Moskowitzova, B Shin, D Blitzer… - Mitochondrion, 2019 - Elsevier
Previously, we have demonstrated that the transplantation of autologous mitochondria is
cardioprotective. No immune or autoimmune response was detectable following the single …

Prospects of mitochondrial transplantation in clinical medicine: Aspirations and challenges

S Hosseinian, PA Pour, A Kheradvar - Mitochondrion, 2022 - Elsevier
Mitochondria, known as the powerhouse of the cell, are at the center of healthy physiology
and provide cells with energy in the form of ATP. These unique organelles are also …

[HTML][HTML] Mitochondrial transplantation ameliorates ischemia/reperfusion-induced kidney injury in rat

H Jabbari, AM Roushandeh, MK Rostami… - … et Biophysica Acta (BBA …, 2020 - Elsevier
No real therapeutic modality is currently available for Acute kidney injury (AKI) and if any,
they are mainly supportive in nature. Therefore, developing a new therapeutic strategy is …

Astrocyte mitochondria: Central players and potential therapeutic targets for neurodegenerative diseases and injury

JL Gollihue, CM Norris - Ageing research reviews, 2020 - Elsevier
Mitochondrial function has long been the focus of many therapeutic strategies for
ameliorating age-related neurodegeneration and cognitive decline. Historically, the role of …

Human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in TBI models through rescuing neuronal …

C Bamshad, MH Roudkenar, M Abedinzade… - International …, 2023 - Elsevier
Each year, traumatic brain injury (TBI) causes a high rate of mortality throughout the world
and those who survive have lasting disabilities. Given that the brain is a particularly dynamic …

Mitochondrial transplantation as a potential and novel master key for treatment of various incurable diseases

AM Roushandeh, Y Kuwahara, MH Roudkenar - Cytotechnology, 2019 - Springer
Mitochondria are attractive cellular organelles which are so interesting in both basic and
clinical research, especially after it was found that they were arisen as a bacterial intruder in …